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Obesity and the risk of newly diagnosed asthma in school-age children.
Am J Epidemiol 2003; 158(5):406-15AJ

Abstract

To determine the relation between obesity and new-onset asthma among school-age children, the authors examined longitudinal data from 3,792 participants in the Children's Health Study (Southern California) who were asthma-free at enrollment. New cases of physician-diagnosed asthma, height, weight, lung function, and risk factors for asthma were assessed annually at five school visits between 1993 and 1998. Incidence rates were calculated, and proportional hazards regression models were fitted to estimate the adjusted relative risks of new-onset asthma associated with percentile of body mass index (weight (kg)/height (m)(2)) and indicators of overweight (>85th body mass index percentile) and obesity (>95th body mass index percentile). The risk of new-onset asthma was higher among children who were overweight (relative risk (RR) = 1.52, 95% confidence interval (CI): 1.14, 2.03) or obese (RR = 1.60, 95% CI: 1.08, 2.36). Boys had an increased risk associated with being overweight (RR = 2.06, 95% 1.33, 3.18) in comparison with girls (RR = 1.25, 95% CI: 0.83, 1.88). The effect of being overweight was greater in nonallergic children (RR = 1.77, 95% CI: 1.26, 2.49) than in allergic children (RR = 1.16, 95% CI: 0.63, 2.15). The authors conclude that being overweight is associated with an increased risk of new-onset asthma in boys and in nonallergic children.

Authors+Show Affiliations

Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA. gillilan@usc.eduNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

12936895

Citation

Gilliland, Frank D., et al. "Obesity and the Risk of Newly Diagnosed Asthma in School-age Children." American Journal of Epidemiology, vol. 158, no. 5, 2003, pp. 406-15.
Gilliland FD, Berhane K, Islam T, et al. Obesity and the risk of newly diagnosed asthma in school-age children. Am J Epidemiol. 2003;158(5):406-15.
Gilliland, F. D., Berhane, K., Islam, T., McConnell, R., Gauderman, W. J., Gilliland, S. S., ... Peters, J. M. (2003). Obesity and the risk of newly diagnosed asthma in school-age children. American Journal of Epidemiology, 158(5), pp. 406-15.
Gilliland FD, et al. Obesity and the Risk of Newly Diagnosed Asthma in School-age Children. Am J Epidemiol. 2003 Sep 1;158(5):406-15. PubMed PMID: 12936895.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Obesity and the risk of newly diagnosed asthma in school-age children. AU - Gilliland,Frank D, AU - Berhane,Kiros, AU - Islam,Talat, AU - McConnell,Rob, AU - Gauderman,W James, AU - Gilliland,Susan S, AU - Avol,Edward, AU - Peters,John M, PY - 2003/8/26/pubmed PY - 2003/9/26/medline PY - 2003/8/26/entrez SP - 406 EP - 15 JF - American journal of epidemiology JO - Am. J. Epidemiol. VL - 158 IS - 5 N2 - To determine the relation between obesity and new-onset asthma among school-age children, the authors examined longitudinal data from 3,792 participants in the Children's Health Study (Southern California) who were asthma-free at enrollment. New cases of physician-diagnosed asthma, height, weight, lung function, and risk factors for asthma were assessed annually at five school visits between 1993 and 1998. Incidence rates were calculated, and proportional hazards regression models were fitted to estimate the adjusted relative risks of new-onset asthma associated with percentile of body mass index (weight (kg)/height (m)(2)) and indicators of overweight (>85th body mass index percentile) and obesity (>95th body mass index percentile). The risk of new-onset asthma was higher among children who were overweight (relative risk (RR) = 1.52, 95% confidence interval (CI): 1.14, 2.03) or obese (RR = 1.60, 95% CI: 1.08, 2.36). Boys had an increased risk associated with being overweight (RR = 2.06, 95% 1.33, 3.18) in comparison with girls (RR = 1.25, 95% CI: 0.83, 1.88). The effect of being overweight was greater in nonallergic children (RR = 1.77, 95% CI: 1.26, 2.49) than in allergic children (RR = 1.16, 95% CI: 0.63, 2.15). The authors conclude that being overweight is associated with an increased risk of new-onset asthma in boys and in nonallergic children. SN - 0002-9262 UR - https://www.unboundmedicine.com/medline/citation/12936895/Obesity_and_the_risk_of_newly_diagnosed_asthma_in_school_age_children_ L2 - https://academic.oup.com/aje/article-lookup/doi/10.1093/aje/kwg175 DB - PRIME DP - Unbound Medicine ER -