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Gulf War veterans and Iraqi nerve agents at Khamisiyah: postwar hospitalization data revisited.
Am J Epidemiol. 2003 Sep 01; 158(5):457-67.AJ

Abstract

Chemical warfare agents were demolished by US soldiers at Khamisiyah, Iraq, in March 1991. The authors investigated postwar morbidity for Gulf War veterans, contrasting those who may have been exposed to low gaseous levels of nerve agents and those unlikely to have been exposed. Cox regression modeling was performed for hospitalizations from all causes and hospitalizations from diagnoses within 15 categories during the period March 10, 1991, through December 31, 2000, for the duration of active-duty status. After adjustment for all variables in the model, only two of 37 models suggested that personnel possibly exposed to subclinical doses of nerve agents might be at increased risk for hospitalization from circulatory diseases, specifically cardiac dysrhythmias. Of the 724 hospitalizations for cardiac dysrhythmias, 203 were in the potentially exposed group, slightly higher than expected (risk ratio = 1.23, 95% confidence interval: 1.04, 1.44). The increase was small in comparison with potential observational variability, but the findings are provocative and warrant further evaluation. Veterans possibly exposed to nerve agents released by the Khamisiyah demolition were not found to be at increased risk for hospitalizations from any other chronic diseases nearly 10 years after the Gulf War.

Authors+Show Affiliations

Department of Defense Center for Deployment Health Research, Naval Health Research Center, San Diego, CA 92186, USA. Smith@nhrc.navy.milNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

12936901

Citation

Smith, Tyler C., et al. "Gulf War Veterans and Iraqi Nerve Agents at Khamisiyah: Postwar Hospitalization Data Revisited." American Journal of Epidemiology, vol. 158, no. 5, 2003, pp. 457-67.
Smith TC, Gray GC, Weir JC, et al. Gulf War veterans and Iraqi nerve agents at Khamisiyah: postwar hospitalization data revisited. Am J Epidemiol. 2003;158(5):457-67.
Smith, T. C., Gray, G. C., Weir, J. C., Heller, J. M., & Ryan, M. A. (2003). Gulf War veterans and Iraqi nerve agents at Khamisiyah: postwar hospitalization data revisited. American Journal of Epidemiology, 158(5), 457-67.
Smith TC, et al. Gulf War Veterans and Iraqi Nerve Agents at Khamisiyah: Postwar Hospitalization Data Revisited. Am J Epidemiol. 2003 Sep 1;158(5):457-67. PubMed PMID: 12936901.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Gulf War veterans and Iraqi nerve agents at Khamisiyah: postwar hospitalization data revisited. AU - Smith,Tyler C, AU - Gray,Gregory C, AU - Weir,J Christopher, AU - Heller,Jack M, AU - Ryan,Margaret A K, PY - 2003/8/26/pubmed PY - 2003/9/26/medline PY - 2003/8/26/entrez SP - 457 EP - 67 JF - American journal of epidemiology JO - Am J Epidemiol VL - 158 IS - 5 N2 - Chemical warfare agents were demolished by US soldiers at Khamisiyah, Iraq, in March 1991. The authors investigated postwar morbidity for Gulf War veterans, contrasting those who may have been exposed to low gaseous levels of nerve agents and those unlikely to have been exposed. Cox regression modeling was performed for hospitalizations from all causes and hospitalizations from diagnoses within 15 categories during the period March 10, 1991, through December 31, 2000, for the duration of active-duty status. After adjustment for all variables in the model, only two of 37 models suggested that personnel possibly exposed to subclinical doses of nerve agents might be at increased risk for hospitalization from circulatory diseases, specifically cardiac dysrhythmias. Of the 724 hospitalizations for cardiac dysrhythmias, 203 were in the potentially exposed group, slightly higher than expected (risk ratio = 1.23, 95% confidence interval: 1.04, 1.44). The increase was small in comparison with potential observational variability, but the findings are provocative and warrant further evaluation. Veterans possibly exposed to nerve agents released by the Khamisiyah demolition were not found to be at increased risk for hospitalizations from any other chronic diseases nearly 10 years after the Gulf War. SN - 0002-9262 UR - https://www.unboundmedicine.com/medline/citation/12936901/Gulf_War_veterans_and_Iraqi_nerve_agents_at_Khamisiyah:_postwar_hospitalization_data_revisited_ L2 - https://academic.oup.com/aje/article-lookup/doi/10.1093/aje/kwg178 DB - PRIME DP - Unbound Medicine ER -