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[Dementia and Lewy bodies].
Rev Neurol. 2003 Jul 16-31; 37(2):127-30.RN

Abstract

Consensus diagnostic criteria for dementia with Lewy bodies (DLB) proposed in 1996 have provided a useful foundation for research in the field. As a clinicopathologically defined entity, DLB has overlapping features of both Alzheimer s disease (AD) and Parkinson's disease (PD). Consensus criteria for DLB distinguish it from PD dementia by the earlier appearance of motor signs in the latter. Studies evaluating the standardized clinical diagnostic criteria for DLB have generally found them to be highly predictive of Lewy body pathology. However, many cases with Lewy body pathology and concomitant pathological features of AD elude clinical detection. Emerging data suggests that AD pathological features mask the clinical expression of concomitant Lewy body pathology, and that DLB and PD dementia may be more similar than distinct.

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Authors+Show Affiliations

Kaufer D
University of Pittsburgh Alzheimer Disease Research Center, Pittsburgh, PA 15213, USA. dkaufer@pitt.edu

MeSH

Alzheimer DiseaseBrainDiagnosis, DifferentialHallucinationsHumansLewy Body DiseaseMuscle RigidityParkinson DiseaseProspective StudiesRetrospective StudiesSensitivity and Specificity

Pub Type(s)

Comparative Study
English Abstract
Journal Article
Review

Language

spa

PubMed ID

12938071

Citation

Kaufer, D. "[Dementia and Lewy Bodies]." Revista De Neurologia, vol. 37, no. 2, 2003, pp. 127-30.
Kaufer D. [Dementia and Lewy bodies]. Rev Neurol. 2003;37(2):127-30.
Kaufer, D. (2003). [Dementia and Lewy bodies]. Revista De Neurologia, 37(2), 127-30.
Kaufer D. [Dementia and Lewy Bodies]. Rev Neurol. 2003 Jul 16-31;37(2):127-30. PubMed PMID: 12938071.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Dementia and Lewy bodies]. A1 - Kaufer,D, PY - 2003/8/26/pubmed PY - 2003/10/30/medline PY - 2003/8/26/entrez SP - 127 EP - 30 JF - Revista de neurologia JO - Rev Neurol VL - 37 IS - 2 N2 - Consensus diagnostic criteria for dementia with Lewy bodies (DLB) proposed in 1996 have provided a useful foundation for research in the field. As a clinicopathologically defined entity, DLB has overlapping features of both Alzheimer s disease (AD) and Parkinson's disease (PD). Consensus criteria for DLB distinguish it from PD dementia by the earlier appearance of motor signs in the latter. Studies evaluating the standardized clinical diagnostic criteria for DLB have generally found them to be highly predictive of Lewy body pathology. However, many cases with Lewy body pathology and concomitant pathological features of AD elude clinical detection. Emerging data suggests that AD pathological features mask the clinical expression of concomitant Lewy body pathology, and that DLB and PD dementia may be more similar than distinct. SN - 0210-0010 UR - https://www.unboundmedicine.com/medline/citation/12938071/[Dementia_and_Lewy_bodies]_ L2 - http://www.revneurol.com/LinkOut/formMedLine.asp?Refer=2002442&Revista=Revneurol DB - PRIME DP - Unbound Medicine ER -