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[Our caseload in Fournier's disease].
Arch Esp Urol. 1992 Dec; 45(10):993-6.AE

Abstract

We reviewed the records of 17 cases of Fournier's gangrene that had been diagnosed and treated in the Urology Service of the Marques de Valdecilla Hospital from 1982-1991. The series comprised male patients aged 32 to 77. Eleven cases (64.7%) were due to a known cause, above all infection. Most of the patients had factors that predisposed to the development and progression of the disease, predominantly diabetes mellitus (5 cases, 29.4%). The clinical features frequently corresponded to those of acute infection, with high fever, chills, pain, nausea and vomiting that could progress to a septic state. The local symptoms and signs included pain, swelling, erythema and necrosis, depending on the compromised area. Infection was usually caused by Gram-negative bacteria, particularly E. coli, although Gram-positive bacteria and anaerobes have been observed. Mixed bacterial infections have also been observed. Treatment must be instituted early using a combination of broad spectrum antibiotics that cover both aerobes and anaerobes, and wide surgical debridement of the compromised area. In some cases hyperbaric oxygen therapy may be warranted. The disease continues to be severe. In the present series, the outcome was favorable in 12 cases (70.5%) and there were 5 deaths (29.4%).

Authors+Show Affiliations

Servicio de Urología, Hospital Universitario Marqués de Valdecilla, Santander, Cantabria, España.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

spa

PubMed ID

1294042

Citation

Monge Mirallas, J M., et al. "[Our Caseload in Fournier's Disease]." Archivos Espanoles De Urologia, vol. 45, no. 10, 1992, pp. 993-6.
Monge Mirallas JM, Portillo Martín JA, Martín García B, et al. [Our caseload in Fournier's disease]. Arch Esp Urol. 1992;45(10):993-6.
Monge Mirallas, J. M., Portillo Martín, J. A., Martín García, B., Hernández Rodríguez, R., Correas Gómez, M. A., Gutiérrez Baños, J. L., Fernández Gómez, J. M., & Concepción Masip, T. (1992). [Our caseload in Fournier's disease]. Archivos Espanoles De Urologia, 45(10), 993-6.
Monge Mirallas JM, et al. [Our Caseload in Fournier's Disease]. Arch Esp Urol. 1992;45(10):993-6. PubMed PMID: 1294042.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Our caseload in Fournier's disease]. AU - Monge Mirallas,J M, AU - Portillo Martín,J A, AU - Martín García,B, AU - Hernández Rodríguez,R, AU - Correas Gómez,M A, AU - Gutiérrez Baños,J L, AU - Fernández Gómez,J M, AU - Concepción Masip,T, PY - 1992/12/1/pubmed PY - 1992/12/1/medline PY - 1992/12/1/entrez SP - 993 EP - 6 JF - Archivos espanoles de urologia JO - Arch Esp Urol VL - 45 IS - 10 N2 - We reviewed the records of 17 cases of Fournier's gangrene that had been diagnosed and treated in the Urology Service of the Marques de Valdecilla Hospital from 1982-1991. The series comprised male patients aged 32 to 77. Eleven cases (64.7%) were due to a known cause, above all infection. Most of the patients had factors that predisposed to the development and progression of the disease, predominantly diabetes mellitus (5 cases, 29.4%). The clinical features frequently corresponded to those of acute infection, with high fever, chills, pain, nausea and vomiting that could progress to a septic state. The local symptoms and signs included pain, swelling, erythema and necrosis, depending on the compromised area. Infection was usually caused by Gram-negative bacteria, particularly E. coli, although Gram-positive bacteria and anaerobes have been observed. Mixed bacterial infections have also been observed. Treatment must be instituted early using a combination of broad spectrum antibiotics that cover both aerobes and anaerobes, and wide surgical debridement of the compromised area. In some cases hyperbaric oxygen therapy may be warranted. The disease continues to be severe. In the present series, the outcome was favorable in 12 cases (70.5%) and there were 5 deaths (29.4%). SN - 0004-0614 UR - https://www.unboundmedicine.com/medline/citation/1294042/[Our_caseload_in_Fournier's_disease]_ DB - PRIME DP - Unbound Medicine ER -