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Cigarette smoking and alcohol consumption associated with gastro-oesophageal reflux disease in Japanese men.

Abstract

BACKGROUND

Associations between lifestyle factors and gastro-oesophageal reflux disease (GORD) have been conflicting. We aimed to examine these associations in Japanese men.

METHODS

We performed a cross-sectional study of Japanese male workers who visit a clinic for a routine health check-up and asked them to fill out a self-report questionnaire. Logistic regression was used to calculate odds ratios (OR) with 95% confidence intervals (CI) for GORD, defined as heartburn and/or acid regurgitation at least twice weekly.

RESULTS

Of the 4095 eligible subjects, 276 (6.7%) were diagnosed as having GORD. Current smoking was significantly associated with CORD compared with non-smoking (OR = 1.35, 95% CI, 1.01-1.82). Moderate drinking (16-37 mL/day) and heavy drinking (> or = 38 mL/day) were also associated with GORD, while age and body mass index were not. After adjustment for age, daily alcohol consumption and body mass index, an increase in number of pack-years of cigarette smoking was significantly associated with an increased OR of GORD (P for trend = 0.034), and the OR for persons whose number of pack-years of cigarette smoking was more than 20.1 was 1.45 (CI 1.04-2.04) compared with non-smokers.

CONCLUSION

Cigarette smoking and alcohol consumption are associated with an increased odds ratio for GORD in Japanese men.

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  • Authors+Show Affiliations

    ,

    Dept. of Gastroenterology, Osaka City University Graduate School of Medicine, Osaka, Japan.

    , , , , , , , ,

    Source

    MeSH

    Adult
    Alcohol Drinking
    Body Mass Index
    Cohort Studies
    Cross-Sectional Studies
    Gastroesophageal Reflux
    Health Behavior
    Humans
    Japan
    Life Style
    Male
    Middle Aged
    Odds Ratio
    Regression Analysis
    Risk Factors
    Smoking

    Pub Type(s)

    Journal Article

    Language

    eng

    PubMed ID

    12940431

    Citation

    Watanabe, Y, et al. "Cigarette Smoking and Alcohol Consumption Associated With Gastro-oesophageal Reflux Disease in Japanese Men." Scandinavian Journal of Gastroenterology, vol. 38, no. 8, 2003, pp. 807-11.
    Watanabe Y, Fujiwara Y, Shiba M, et al. Cigarette smoking and alcohol consumption associated with gastro-oesophageal reflux disease in Japanese men. Scand J Gastroenterol. 2003;38(8):807-11.
    Watanabe, Y., Fujiwara, Y., Shiba, M., Watanabe, T., Tominaga, K., Oshitani, N., ... Arakawa, T. (2003). Cigarette smoking and alcohol consumption associated with gastro-oesophageal reflux disease in Japanese men. Scandinavian Journal of Gastroenterology, 38(8), pp. 807-11.
    Watanabe Y, et al. Cigarette Smoking and Alcohol Consumption Associated With Gastro-oesophageal Reflux Disease in Japanese Men. Scand J Gastroenterol. 2003;38(8):807-11. PubMed PMID: 12940431.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Cigarette smoking and alcohol consumption associated with gastro-oesophageal reflux disease in Japanese men. AU - Watanabe,Y, AU - Fujiwara,Y, AU - Shiba,M, AU - Watanabe,T, AU - Tominaga,K, AU - Oshitani,N, AU - Matsumoto,T, AU - Nishikawa,H, AU - Higuchi,K, AU - Arakawa,T, PY - 2003/8/28/pubmed PY - 2003/12/17/medline PY - 2003/8/28/entrez SP - 807 EP - 11 JF - Scandinavian journal of gastroenterology JO - Scand. J. Gastroenterol. VL - 38 IS - 8 N2 - BACKGROUND: Associations between lifestyle factors and gastro-oesophageal reflux disease (GORD) have been conflicting. We aimed to examine these associations in Japanese men. METHODS: We performed a cross-sectional study of Japanese male workers who visit a clinic for a routine health check-up and asked them to fill out a self-report questionnaire. Logistic regression was used to calculate odds ratios (OR) with 95% confidence intervals (CI) for GORD, defined as heartburn and/or acid regurgitation at least twice weekly. RESULTS: Of the 4095 eligible subjects, 276 (6.7%) were diagnosed as having GORD. Current smoking was significantly associated with CORD compared with non-smoking (OR = 1.35, 95% CI, 1.01-1.82). Moderate drinking (16-37 mL/day) and heavy drinking (> or = 38 mL/day) were also associated with GORD, while age and body mass index were not. After adjustment for age, daily alcohol consumption and body mass index, an increase in number of pack-years of cigarette smoking was significantly associated with an increased OR of GORD (P for trend = 0.034), and the OR for persons whose number of pack-years of cigarette smoking was more than 20.1 was 1.45 (CI 1.04-2.04) compared with non-smokers. CONCLUSION: Cigarette smoking and alcohol consumption are associated with an increased odds ratio for GORD in Japanese men. SN - 0036-5521 UR - https://www.unboundmedicine.com/medline/citation/12940431/Cigarette_smoking_and_alcohol_consumption_associated_with_gastro_oesophageal_reflux_disease_in_Japanese_men_ L2 - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=linkout&SEARCH=12940431.ui DB - PRIME DP - Unbound Medicine ER -