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Biological activity of serotonin conjugates from the seeds of Centaurea nigra.
Fitoterapia. 2003 Sep; 74(6):609-12.F

Abstract

Two serotonin conjugates, N-(trans-p-coumaroyl)-serotonin (1) and N-(trans-feruloyl)-serotonin (maoschamine, 2), isolated from the methanol extract of the seeds of Centaurea nigra, have been assessed for antibacterial and free radical scavenging activities. The general toxicity of 1 and 2 has also been determined by the brine shrimp lethality bioassay.

Authors+Show Affiliations

Kumarasamy Y
Phytopharmaceutical Research Laboratory, School of Pharmacy, The Robert Gordon University, Schoolhill, Aberdeen, AB10 1FR, Scotland, UK.
Middleton M
No affiliation info available
Reid RG
No affiliation info available
Nahar L
No affiliation info available
Sarker SD
No affiliation info available

MeSH

AnimalsAnti-Bacterial AgentsArtemiaCentaureaFree Radical ScavengersGram-Negative BacteriaGram-Positive BacteriaHumansLethal Dose 50Microbial Sensitivity TestsPhytotherapyPlant ExtractsSeedsSerotonin

Pub Type(s)

Journal Article

Language

eng

PubMed ID

12946728

Citation

Kumarasamy, Y, et al. "Biological Activity of Serotonin Conjugates From the Seeds of Centaurea Nigra." Fitoterapia, vol. 74, no. 6, 2003, pp. 609-12.
Kumarasamy Y, Middleton M, Reid RG, et al. Biological activity of serotonin conjugates from the seeds of Centaurea nigra. Fitoterapia. 2003;74(6):609-12.
Kumarasamy, Y., Middleton, M., Reid, R. G., Nahar, L., & Sarker, S. D. (2003). Biological activity of serotonin conjugates from the seeds of Centaurea nigra. Fitoterapia, 74(6), 609-12.
Kumarasamy Y, et al. Biological Activity of Serotonin Conjugates From the Seeds of Centaurea Nigra. Fitoterapia. 2003;74(6):609-12. PubMed PMID: 12946728.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Biological activity of serotonin conjugates from the seeds of Centaurea nigra. AU - Kumarasamy,Y, AU - Middleton,M, AU - Reid,R G, AU - Nahar,L, AU - Sarker,S D, PY - 2003/8/30/pubmed PY - 2003/10/11/medline PY - 2003/8/30/entrez SP - 609 EP - 12 JF - Fitoterapia JO - Fitoterapia VL - 74 IS - 6 N2 - Two serotonin conjugates, N-(trans-p-coumaroyl)-serotonin (1) and N-(trans-feruloyl)-serotonin (maoschamine, 2), isolated from the methanol extract of the seeds of Centaurea nigra, have been assessed for antibacterial and free radical scavenging activities. The general toxicity of 1 and 2 has also been determined by the brine shrimp lethality bioassay. SN - 0367-326X UR - https://www.unboundmedicine.com/medline/citation/12946728/Biological_activity_of_serotonin_conjugates_from_the_seeds_of_Centaurea_nigra_ DB - PRIME DP - Unbound Medicine ER -