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Comparative studies of live neonates in maternal sickle cell haemoglobinopathy in Ghana.
Trop Geogr Med. 1992 Oct; 44(4):312-6.TG

Abstract

This study assessed the current status of live neonates born to sickle cell mothers when compared with those of normal (control) women. Birth weight, placental weight, fetoplacental ratio, and gestational age for live neonates in singleton births by twenty-nine haemoglobin SS (HbSS), fifty-two haemoglobin SC (HbSC), and fifty-one (normal) haemoglobin AA (HbAA) mothers were statistically compared. Neonates of HbSS mothers had a statistically lower than normal mean birth weight and gestational age, but only a shorter mean gestation significantly distinguished those of the HbSC and HbAA mothers. Inferentially, neonates delivered by HbSS women were both underweight and preterm, whereas those of HbSC women were preterm but not underweight, and apparently large for gestational age (LGA). No statistical differences were found between neonates in terms of placental weights or fetoplacental ratios.

Authors+Show Affiliations

Department of Anatomy, University of Ghana Medical School, Accra.No affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

1295139

Citation

Addai, F K., et al. "Comparative Studies of Live Neonates in Maternal Sickle Cell Haemoglobinopathy in Ghana." Tropical and Geographical Medicine, vol. 44, no. 4, 1992, pp. 312-6.
Addai FK, Wilson JB, Quashie FJ. Comparative studies of live neonates in maternal sickle cell haemoglobinopathy in Ghana. Trop Geogr Med. 1992;44(4):312-6.
Addai, F. K., Wilson, J. B., & Quashie, F. J. (1992). Comparative studies of live neonates in maternal sickle cell haemoglobinopathy in Ghana. Tropical and Geographical Medicine, 44(4), 312-6.
Addai FK, Wilson JB, Quashie FJ. Comparative Studies of Live Neonates in Maternal Sickle Cell Haemoglobinopathy in Ghana. Trop Geogr Med. 1992;44(4):312-6. PubMed PMID: 1295139.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Comparative studies of live neonates in maternal sickle cell haemoglobinopathy in Ghana. AU - Addai,F K, AU - Wilson,J B, AU - Quashie,F J, PY - 1992/10/1/pubmed PY - 1992/10/1/medline PY - 1992/10/1/entrez KW - Africa KW - Africa South Of The Sahara KW - Biology KW - Birth Weight KW - Body Weight KW - Case Control Studies KW - Data Analysis KW - Developing Countries KW - Diseases KW - English Speaking Africa KW - Fetus KW - Gestational Age KW - Ghana KW - Hematological Effects KW - Hemic System KW - Hemoglobin Level KW - Hereditary Diseases KW - Low Birth Weight KW - Physiology KW - Pregnancy KW - Pregnancy Outcomes KW - Reproduction KW - Research Methodology KW - Retrospective Studies KW - Studies KW - Western Africa SP - 312 EP - 6 JF - Tropical and geographical medicine JO - Trop Geogr Med VL - 44 IS - 4 N2 - This study assessed the current status of live neonates born to sickle cell mothers when compared with those of normal (control) women. Birth weight, placental weight, fetoplacental ratio, and gestational age for live neonates in singleton births by twenty-nine haemoglobin SS (HbSS), fifty-two haemoglobin SC (HbSC), and fifty-one (normal) haemoglobin AA (HbAA) mothers were statistically compared. Neonates of HbSS mothers had a statistically lower than normal mean birth weight and gestational age, but only a shorter mean gestation significantly distinguished those of the HbSC and HbAA mothers. Inferentially, neonates delivered by HbSS women were both underweight and preterm, whereas those of HbSC women were preterm but not underweight, and apparently large for gestational age (LGA). No statistical differences were found between neonates in terms of placental weights or fetoplacental ratios. SN - 0041-3232 UR - https://www.unboundmedicine.com/medline/citation/1295139/Comparative_studies_of_live_neonates_in_maternal_sickle_cell_haemoglobinopathy_in_Ghana_ DB - PRIME DP - Unbound Medicine ER -