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Leucocyte migration inhibition factor (L-MIF) in malnourished Nigerian children.

Abstract

Leucocyte Migration Inhibition Factor (L-MIF) was measured in 41 children with marasmus, 19 with kwashiorkor, 5 with marasmic-kwashiorkor and 35 well-fed healthy children serving as controls. For L-MIF assay, two different antigens (live attenuated measles virus vaccine and diptheria pertussis tetanus (DPT) vaccine were used. Percentage migration indices obtained with the two antigens were significantly higher in the malnourished than in the well-fed healthy sex and age-matched controls (P < 0.01). The total serum protein and albumin concentrations were significantly reduced in the malnourished children compared with the controls (P < 0.01). Mean total leucocyte numbers were not significantly different in marasmic and marasmic-kwashiorkor children compared with the controls (P > 0.21).

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Authors+Show Affiliations

,

Department of Chemical Pathology, University College Hospital, Ibadan, Nigeria.

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Source

MeSH

Blood Proteins
Case-Control Studies
Child
Child Nutrition Disorders
Humans
Immunity, Cellular
Kwashiorkor
Leukocyte Count
Leukocyte Migration-Inhibitory Factors
Lymphocyte Activation
Nigeria
Nutrition Assessment
Nutritional Status
Protein-Energy Malnutrition
Serum Albumin
Severity of Illness Index

Pub Type(s)

Journal Article

Language

eng

PubMed ID

12953981

Citation

Fongwo, N P., et al. "Leucocyte Migration Inhibition Factor (L-MIF) in Malnourished Nigerian Children." African Journal of Medicine and Medical Sciences, vol. 28, no. 1-2, 1999, pp. 17-20.
Fongwo NP, Arinola OG, Salimonu LS. Leucocyte migration inhibition factor (L-MIF) in malnourished Nigerian children. Afr J Med Med Sci. 1999;28(1-2):17-20.
Fongwo, N. P., Arinola, O. G., & Salimonu, L. S. (1999). Leucocyte migration inhibition factor (L-MIF) in malnourished Nigerian children. African Journal of Medicine and Medical Sciences, 28(1-2), pp. 17-20.
Fongwo NP, Arinola OG, Salimonu LS. Leucocyte Migration Inhibition Factor (L-MIF) in Malnourished Nigerian Children. Afr J Med Med Sci. 1999;28(1-2):17-20. PubMed PMID: 12953981.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Leucocyte migration inhibition factor (L-MIF) in malnourished Nigerian children. AU - Fongwo,N P, AU - Arinola,O G, AU - Salimonu,L S, PY - 2003/9/5/pubmed PY - 2003/10/3/medline PY - 2003/9/5/entrez SP - 17 EP - 20 JF - African journal of medicine and medical sciences JO - Afr J Med Med Sci VL - 28 IS - 1-2 N2 - Leucocyte Migration Inhibition Factor (L-MIF) was measured in 41 children with marasmus, 19 with kwashiorkor, 5 with marasmic-kwashiorkor and 35 well-fed healthy children serving as controls. For L-MIF assay, two different antigens (live attenuated measles virus vaccine and diptheria pertussis tetanus (DPT) vaccine were used. Percentage migration indices obtained with the two antigens were significantly higher in the malnourished than in the well-fed healthy sex and age-matched controls (P < 0.01). The total serum protein and albumin concentrations were significantly reduced in the malnourished children compared with the controls (P < 0.01). Mean total leucocyte numbers were not significantly different in marasmic and marasmic-kwashiorkor children compared with the controls (P > 0.21). SN - 0309-3913 UR - https://www.unboundmedicine.com/medline/citation/12953981/Leucocyte_migration_inhibition_factor__L_MIF__in_malnourished_Nigerian_children_ L2 - https://medlineplus.gov/childnutrition.html DB - PRIME DP - Unbound Medicine ER -