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Plasma electrolytes, total cholesterol, liver enzymes, and selected antioxidant status in protein energy malnutrition.
Afr J Med Med Sci 1999 Mar-Jun; 28(1-2):81-5AJ

Abstract

Golden and Ramdath proposed the free radical theory of kwashiorkor, suggesting that the changes seen in kwashiorkor may be the result of an imbalance between the production and safe disposal of free radicals. In malnourished children, mineral metabolism and antioxidant status need renewed attention especially in relation to cause and functional significance of the changes in concentration of these substances. In the present study, the modified Wellcome classification was used to classify the protein energy malnourished children into kwashiorkor marasmic-kwashiorkor, marasmus and underweight. Twenty-six healthy and normal children were used as controls. Standard procedures were used for the analyses of the biochemical parameters. Our results showed that plasma total cholesterol, sodium, potassium and bicarbonate, beta-carotene, retinol and uric acid were significantly lower in the malnourished group than the control group (P < 0.05), while transaminases were significantly increased in the malnourished group (P < 0.05). These findings suggest an altered electrolyte and antioxidant status in protein energy malnutrition.

Authors+Show Affiliations

Department of Chemical Pathology, College of Medicine, University of Ibadan, Ibadan, Nigeria.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

12953993

Citation

Etukudo, M H., et al. "Plasma Electrolytes, Total Cholesterol, Liver Enzymes, and Selected Antioxidant Status in Protein Energy Malnutrition." African Journal of Medicine and Medical Sciences, vol. 28, no. 1-2, 1999, pp. 81-5.
Etukudo MH, Agbedana EO, Akinyinka OO, et al. Plasma electrolytes, total cholesterol, liver enzymes, and selected antioxidant status in protein energy malnutrition. Afr J Med Med Sci. 1999;28(1-2):81-5.
Etukudo, M. H., Agbedana, E. O., Akinyinka, O. O., & Osifo, B. O. (1999). Plasma electrolytes, total cholesterol, liver enzymes, and selected antioxidant status in protein energy malnutrition. African Journal of Medicine and Medical Sciences, 28(1-2), pp. 81-5.
Etukudo MH, et al. Plasma Electrolytes, Total Cholesterol, Liver Enzymes, and Selected Antioxidant Status in Protein Energy Malnutrition. Afr J Med Med Sci. 1999;28(1-2):81-5. PubMed PMID: 12953993.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Plasma electrolytes, total cholesterol, liver enzymes, and selected antioxidant status in protein energy malnutrition. AU - Etukudo,M H, AU - Agbedana,E O, AU - Akinyinka,O O, AU - Osifo,B O, PY - 2003/9/5/pubmed PY - 2003/10/3/medline PY - 2003/9/5/entrez SP - 81 EP - 5 JF - African journal of medicine and medical sciences JO - Afr J Med Med Sci VL - 28 IS - 1-2 N2 - Golden and Ramdath proposed the free radical theory of kwashiorkor, suggesting that the changes seen in kwashiorkor may be the result of an imbalance between the production and safe disposal of free radicals. In malnourished children, mineral metabolism and antioxidant status need renewed attention especially in relation to cause and functional significance of the changes in concentration of these substances. In the present study, the modified Wellcome classification was used to classify the protein energy malnourished children into kwashiorkor marasmic-kwashiorkor, marasmus and underweight. Twenty-six healthy and normal children were used as controls. Standard procedures were used for the analyses of the biochemical parameters. Our results showed that plasma total cholesterol, sodium, potassium and bicarbonate, beta-carotene, retinol and uric acid were significantly lower in the malnourished group than the control group (P < 0.05), while transaminases were significantly increased in the malnourished group (P < 0.05). These findings suggest an altered electrolyte and antioxidant status in protein energy malnutrition. SN - 0309-3913 UR - https://www.unboundmedicine.com/medline/citation/12953993/Plasma_electrolytes_total_cholesterol_liver_enzymes_and_selected_antioxidant_status_in_protein_energy_malnutrition_ L2 - https://medlineplus.gov/childnutrition.html DB - PRIME DP - Unbound Medicine ER -