Isolation and characterization of viruses related to the SARS coronavirus from animals in southern China.Science. 2003 Oct 10; 302(5643):276-8.Sci
Abstract
A novel coronavirus (SCoV) is the etiological agent of severe acute respiratory syndrome (SARS). SCoV-like viruses were isolated from Himalayan palm civets found in a live-animal market in Guangdong, China. Evidence of virus infection was also detected in other animals (including a raccoon dog, Nyctereutes procyonoides) and in humans working at the same market. All the animal isolates retain a 29-nucleotide sequence that is not found in most human isolates. The detection of SCoV-like viruses in small, live wild mammals in a retail market indicates a route of interspecies transmission, although the natural reservoir is not known.
MeSH
Amino Acid SequenceAnimalsAnimals, WildAntibodies, ViralBlotting, WesternCarnivoraChinaCoronavirusCoronavirus InfectionsDisease ReservoirsFecesGenome, ViralHumansMembrane GlycoproteinsMolecular Sequence DataNeutralization TestsNoseOpen Reading FramesPhylogenyPolymorphism, GeneticReverse Transcriptase Polymerase Chain ReactionSevere acute respiratory syndrome-related coronavirusSequence DeletionSequence Homology, Nucleic AcidSpike Glycoprotein, CoronavirusViral Envelope ProteinsViral Proteins
Pub Type(s)
Comparative Study
Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.
Language
eng
PubMed ID
12958366
Citation
Guan, Y, et al. "Isolation and Characterization of Viruses Related to the SARS Coronavirus From Animals in Southern China." Science (New York, N.Y.), vol. 302, no. 5643, 2003, pp. 276-8.
Guan Y, Zheng BJ, He YQ, et al. Isolation and characterization of viruses related to the SARS coronavirus from animals in southern China. Science. 2003;302(5643):276-8.
Guan, Y., Zheng, B. J., He, Y. Q., Liu, X. L., Zhuang, Z. X., Cheung, C. L., Luo, S. W., Li, P. H., Zhang, L. J., Guan, Y. J., Butt, K. M., Wong, K. L., Chan, K. W., Lim, W., Shortridge, K. F., Yuen, K. Y., Peiris, J. S., & Poon, L. L. (2003). Isolation and characterization of viruses related to the SARS coronavirus from animals in southern China. Science (New York, N.Y.), 302(5643), 276-8.
Guan Y, et al. Isolation and Characterization of Viruses Related to the SARS Coronavirus From Animals in Southern China. Science. 2003 Oct 10;302(5643):276-8. PubMed PMID: 12958366.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR
T1 - Isolation and characterization of viruses related to the SARS coronavirus from animals in southern China.
AU - Guan,Y,
AU - Zheng,B J,
AU - He,Y Q,
AU - Liu,X L,
AU - Zhuang,Z X,
AU - Cheung,C L,
AU - Luo,S W,
AU - Li,P H,
AU - Zhang,L J,
AU - Guan,Y J,
AU - Butt,K M,
AU - Wong,K L,
AU - Chan,K W,
AU - Lim,W,
AU - Shortridge,K F,
AU - Yuen,K Y,
AU - Peiris,J S M,
AU - Poon,L L M,
Y1 - 2003/09/04/
PY - 2003/9/6/pubmed
PY - 2003/10/31/medline
PY - 2003/9/6/entrez
SP - 276
EP - 8
JF - Science (New York, N.Y.)
JO - Science
VL - 302
IS - 5643
N2 - A novel coronavirus (SCoV) is the etiological agent of severe acute respiratory syndrome (SARS). SCoV-like viruses were isolated from Himalayan palm civets found in a live-animal market in Guangdong, China. Evidence of virus infection was also detected in other animals (including a raccoon dog, Nyctereutes procyonoides) and in humans working at the same market. All the animal isolates retain a 29-nucleotide sequence that is not found in most human isolates. The detection of SCoV-like viruses in small, live wild mammals in a retail market indicates a route of interspecies transmission, although the natural reservoir is not known.
SN - 1095-9203
UR - https://www.unboundmedicine.com/medline/citation/12958366/Isolation_and_characterization_of_viruses_related_to_the_SARS_coronavirus_from_animals_in_southern_China_
DB - PRIME
DP - Unbound Medicine
ER -
