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Legionnaires' disease outbreak in Murcia, Spain.
Emerg Infect Dis. 2003 Aug; 9(8):915-21.EI

Abstract

An explosive outbreak of Legionnaires' disease occurred in Murcia, Spain, in July 2001. More than 800 suspected cases were reported; 449 these cases were confirmed, which made this the world's largest outbreak of the disease reported to date. Dates of onset for confirmed cases ranged from June 26 to July 19, with a case-fatality rate of 1%. The epidemic curve and geographic pattern from the 600 competed epidemiologic questionnaires indicated an outdoor point-source exposure in the northern part of the city. A case-control study matching 85 patients living outside the city of Murcia with two controls each was undertaken to identify to outbreak source; the epidemiologic investigation implicated the cooling towers at a city hospital. An environmental isolate from these towers with an identical molecular pattern as the clinical isolates was subsequently identified and supported that epidemiologic conclusion.

Authors+Show Affiliations

Regional Health Council of Murcia, Murcia, Spain. anam.garcia9@carm.esNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

12967487

Citation

García-Fulgueiras, Anna, et al. "Legionnaires' Disease Outbreak in Murcia, Spain." Emerging Infectious Diseases, vol. 9, no. 8, 2003, pp. 915-21.
García-Fulgueiras A, Navarro C, Fenoll D, et al. Legionnaires' disease outbreak in Murcia, Spain. Emerging Infect Dis. 2003;9(8):915-21.
García-Fulgueiras, A., Navarro, C., Fenoll, D., García, J., González-Diego, P., Jiménez-Buñuales, T., Rodriguez, M., Lopez, R., Pacheco, F., Ruiz, J., Segovia, M., Balandrón, B., & Pelaz, C. (2003). Legionnaires' disease outbreak in Murcia, Spain. Emerging Infectious Diseases, 9(8), 915-21.
García-Fulgueiras A, et al. Legionnaires' Disease Outbreak in Murcia, Spain. Emerging Infect Dis. 2003;9(8):915-21. PubMed PMID: 12967487.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Legionnaires' disease outbreak in Murcia, Spain. AU - García-Fulgueiras,Anna, AU - Navarro,Carmen, AU - Fenoll,Daniel, AU - García,José, AU - González-Diego,Paulino, AU - Jiménez-Buñuales,Teresa, AU - Rodriguez,Miguel, AU - Lopez,Rosa, AU - Pacheco,Francisco, AU - Ruiz,Joaquín, AU - Segovia,Manuel, AU - Balandrón,Beatriz, AU - Pelaz,Carmen, PY - 2003/9/12/pubmed PY - 2003/11/6/medline PY - 2003/9/12/entrez SP - 915 EP - 21 JF - Emerging infectious diseases JO - Emerging Infect. Dis. VL - 9 IS - 8 N2 - An explosive outbreak of Legionnaires' disease occurred in Murcia, Spain, in July 2001. More than 800 suspected cases were reported; 449 these cases were confirmed, which made this the world's largest outbreak of the disease reported to date. Dates of onset for confirmed cases ranged from June 26 to July 19, with a case-fatality rate of 1%. The epidemic curve and geographic pattern from the 600 competed epidemiologic questionnaires indicated an outdoor point-source exposure in the northern part of the city. A case-control study matching 85 patients living outside the city of Murcia with two controls each was undertaken to identify to outbreak source; the epidemiologic investigation implicated the cooling towers at a city hospital. An environmental isolate from these towers with an identical molecular pattern as the clinical isolates was subsequently identified and supported that epidemiologic conclusion. SN - 1080-6040 UR - https://www.unboundmedicine.com/medline/citation/12967487/full_citation L2 - https://www.cdc.gov/ncidod/EID/vol9no8/03-0037.htm DB - PRIME DP - Unbound Medicine ER -