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[Postprandial hyperglycemia. Postprandial blood glucose fluctuations, cardiovascular disease and late diabetic complications].
Ugeskr Laeger. 2003 Aug 11; 165(33):3149-53.UL

Abstract

Epidemiological studies have suggested that postprandial hyperglycaemia may be a unique risk factor for development of cardiovascular disease, although the predictive value has been minor or disappeared after compensation for other cardiovascular risk factors. Pathophysiological studies have demonstrated that acute changes in blood glucose may induce changes predisposing for development of microangiopathy in the retina, the kidneys and the nerves. Studies have also shown that postprandial hyperglycaemia may be a risk factor for the development of atherosclerosis. No randomised controlled trials have focused on specific treatment of postprandial hyperglycaemia. Therefore, the importance of postprandial hyperglycaemia for development of diabetic complications and atherosclerosis is unclear.

Authors+Show Affiliations

Madsbad S
H:S Hvidovre Hospital, Medicinsk Center, Endokrinologisk Klinik, DK-2650 Hvidovre.
Brock B
No affiliation info available
Schmitz O
No affiliation info available

MeSH

ArteriosclerosisBlood GlucoseCardiovascular DiseasesDiabetes ComplicationsDiabetes MellitusDiabetic AngiopathiesHumansHyperglycemiaPostprandial PeriodRisk Factors

Pub Type(s)

English Abstract
Journal Article
Review

Language

dan

PubMed ID

12968409

Citation

Madsbad, Sten, et al. "[Postprandial Hyperglycemia. Postprandial Blood Glucose Fluctuations, Cardiovascular Disease and Late Diabetic Complications]." Ugeskrift for Laeger, vol. 165, no. 33, 2003, pp. 3149-53.
Madsbad S, Brock B, Schmitz O. [Postprandial hyperglycemia. Postprandial blood glucose fluctuations, cardiovascular disease and late diabetic complications]. Ugeskr Laeger. 2003;165(33):3149-53.
Madsbad, S., Brock, B., & Schmitz, O. (2003). [Postprandial hyperglycemia. Postprandial blood glucose fluctuations, cardiovascular disease and late diabetic complications]. Ugeskrift for Laeger, 165(33), 3149-53.
Madsbad S, Brock B, Schmitz O. [Postprandial Hyperglycemia. Postprandial Blood Glucose Fluctuations, Cardiovascular Disease and Late Diabetic Complications]. Ugeskr Laeger. 2003 Aug 11;165(33):3149-53. PubMed PMID: 12968409.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Postprandial hyperglycemia. Postprandial blood glucose fluctuations, cardiovascular disease and late diabetic complications]. AU - Madsbad,Sten, AU - Brock,Birgitte, AU - Schmitz,Ole, PY - 2003/9/13/pubmed PY - 2003/10/8/medline PY - 2003/9/13/entrez SP - 3149 EP - 53 JF - Ugeskrift for laeger JO - Ugeskr Laeger VL - 165 IS - 33 N2 - Epidemiological studies have suggested that postprandial hyperglycaemia may be a unique risk factor for development of cardiovascular disease, although the predictive value has been minor or disappeared after compensation for other cardiovascular risk factors. Pathophysiological studies have demonstrated that acute changes in blood glucose may induce changes predisposing for development of microangiopathy in the retina, the kidneys and the nerves. Studies have also shown that postprandial hyperglycaemia may be a risk factor for the development of atherosclerosis. No randomised controlled trials have focused on specific treatment of postprandial hyperglycaemia. Therefore, the importance of postprandial hyperglycaemia for development of diabetic complications and atherosclerosis is unclear. SN - 0041-5782 UR - https://www.unboundmedicine.com/medline/citation/12968409/[Postprandial_hyperglycemia__Postprandial_blood_glucose_fluctuations_cardiovascular_disease_and_late_diabetic_complications]_ DB - PRIME DP - Unbound Medicine ER -