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Disease-specific health status after stent-assisted percutaneous coronary intervention and coronary artery bypass surgery: one-year results from the Stent or Surgery trial.
Circulation 2003; 108(14):1694-700Circ

Abstract

BACKGROUND

Functional status and quality of life are important outcomes in the evaluation of revascularization approaches for symptomatic coronary artery disease. Few data are available regarding the comparative improvement in disease-specific health status after CABG versus percutaneous coronary intervention (PCI) in the era of coronary stenting.

METHODS AND RESULTS

Cardiac-specific health status was evaluated at baseline and at 6 and 12 months after intervention with the Seattle Angina Questionnaire (SAQ) in patients randomized to stent-assisted PCI (n=488) versus CABG (n=500) in the Stent or Surgery trial. Scores for physical limitation, angina frequency, and quality of life improved significantly for both treatment groups at 6 months (range of improvement from 13.6 to 34.7 points) and 12 months (14.3 to 38.2 points; all P<0.001). CABG patients had greater improvement than those assigned to PCI, although the magnitude of the difference decreased over time (difference at 6 months, 4.03 to 6.48 points; 12 months, 2.05 to 2.93 points). A component of this reduction is accounted for by PCI-arm patients who required repeat intervention. Differences between treatment groups were greatest for the 6-month angina frequency scores (difference=6.48 points; 95% CI 3.96 to 8.99). Overall, treatment satisfaction was high and did not differ significantly between groups.

CONCLUSIONS

Both CABG and stent-assisted PCI dramatically improved cardiac-related health status in patients with multivessel disease at 6- and 12-month follow-up. During the first postprocedure year, patients' angina burden and physical limitations were alleviated to a greater extent with CABG.

Authors+Show Affiliations

Division of Cardiology, Emory University School of Medicine, Atlanta, Ga 30306, USA.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Comparative Study
Journal Article
Multicenter Study
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

12975252

Citation

Zhang, Zefeng, et al. "Disease-specific Health Status After Stent-assisted Percutaneous Coronary Intervention and Coronary Artery Bypass Surgery: One-year Results From the Stent or Surgery Trial." Circulation, vol. 108, no. 14, 2003, pp. 1694-700.
Zhang Z, Mahoney EM, Stables RH, et al. Disease-specific health status after stent-assisted percutaneous coronary intervention and coronary artery bypass surgery: one-year results from the Stent or Surgery trial. Circulation. 2003;108(14):1694-700.
Zhang, Z., Mahoney, E. M., Stables, R. H., Booth, J., Nugara, F., Spertus, J. A., & Weintraub, W. S. (2003). Disease-specific health status after stent-assisted percutaneous coronary intervention and coronary artery bypass surgery: one-year results from the Stent or Surgery trial. Circulation, 108(14), pp. 1694-700.
Zhang Z, et al. Disease-specific Health Status After Stent-assisted Percutaneous Coronary Intervention and Coronary Artery Bypass Surgery: One-year Results From the Stent or Surgery Trial. Circulation. 2003 Oct 7;108(14):1694-700. PubMed PMID: 12975252.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Disease-specific health status after stent-assisted percutaneous coronary intervention and coronary artery bypass surgery: one-year results from the Stent or Surgery trial. AU - Zhang,Zefeng, AU - Mahoney,Elizabeth M, AU - Stables,Rodney H, AU - Booth,Jean, AU - Nugara,Fiona, AU - Spertus,John A, AU - Weintraub,William S, Y1 - 2003/09/15/ PY - 2003/9/17/pubmed PY - 2003/11/5/medline PY - 2003/9/17/entrez SP - 1694 EP - 700 JF - Circulation JO - Circulation VL - 108 IS - 14 N2 - BACKGROUND: Functional status and quality of life are important outcomes in the evaluation of revascularization approaches for symptomatic coronary artery disease. Few data are available regarding the comparative improvement in disease-specific health status after CABG versus percutaneous coronary intervention (PCI) in the era of coronary stenting. METHODS AND RESULTS: Cardiac-specific health status was evaluated at baseline and at 6 and 12 months after intervention with the Seattle Angina Questionnaire (SAQ) in patients randomized to stent-assisted PCI (n=488) versus CABG (n=500) in the Stent or Surgery trial. Scores for physical limitation, angina frequency, and quality of life improved significantly for both treatment groups at 6 months (range of improvement from 13.6 to 34.7 points) and 12 months (14.3 to 38.2 points; all P<0.001). CABG patients had greater improvement than those assigned to PCI, although the magnitude of the difference decreased over time (difference at 6 months, 4.03 to 6.48 points; 12 months, 2.05 to 2.93 points). A component of this reduction is accounted for by PCI-arm patients who required repeat intervention. Differences between treatment groups were greatest for the 6-month angina frequency scores (difference=6.48 points; 95% CI 3.96 to 8.99). Overall, treatment satisfaction was high and did not differ significantly between groups. CONCLUSIONS: Both CABG and stent-assisted PCI dramatically improved cardiac-related health status in patients with multivessel disease at 6- and 12-month follow-up. During the first postprocedure year, patients' angina burden and physical limitations were alleviated to a greater extent with CABG. SN - 1524-4539 UR - https://www.unboundmedicine.com/medline/citation/12975252/Disease_specific_health_status_after_stent_assisted_percutaneous_coronary_intervention_and_coronary_artery_bypass_surgery:_one_year_results_from_the_Stent_or_Surgery_trial_ L2 - http://www.ahajournals.org/doi/full/10.1161/01.CIR.0000087600.83707.FD?url_ver=Z39.88-2003&amp;rfr_id=ori:rid:crossref.org&amp;rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -