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[Changes in the level of humoral response for measles virus in patients with subacute sclerotic panencephalitis during 1984-1989].
Med Dosw Mikrobiol. 1992; 44(3-4):173-85.MD

Abstract

Immunological response to measles virus in serum and cerebro-spinal fluid of 338 patients with subacute sclerotic panencephalitis (SSPE) during the years 1984-1989, was investigated. It was found that mean titer and distribution of results of antibody determination by the hemagglutination inhibition (OZHA) method in patients sera are visibly differing during consecutive years of investigation. Analysis of these parameters in determination by the immunoenzymatic methods (ELISA) has shown their higher stability. Also results of determinations of IgG concentration in sera of patients with SSPE did not demonstrate significant differences between consecutive years of investigation. Systematic decrease of mutual relation between antibodies to measles virus detected by ELISA and OZHA was found. Analysis of local synthesis of antibodies to measles virus in the central nervous system has revealed that it most strongly expressed by hemagglutinin.

Authors+Show Affiliations

Gut W
Zakład Wirusologii PZH w Warszawie.

MeSH

Antibodies, ViralAntibody FormationHumansImmunoglobulin GMeasles virusSubacute Sclerosing Panencephalitis

Pub Type(s)

English Abstract
Journal Article
Research Support, Non-U.S. Gov't

Language

pol

PubMed ID

1305922

Citation

Gut, W. "[Changes in the Level of Humoral Response for Measles Virus in Patients With Subacute Sclerotic Panencephalitis During 1984-1989]." Medycyna Doswiadczalna I Mikrobiologia, vol. 44, no. 3-4, 1992, pp. 173-85.
Gut W. [Changes in the level of humoral response for measles virus in patients with subacute sclerotic panencephalitis during 1984-1989]. Med Dosw Mikrobiol. 1992;44(3-4):173-85.
Gut, W. (1992). [Changes in the level of humoral response for measles virus in patients with subacute sclerotic panencephalitis during 1984-1989]. Medycyna Doswiadczalna I Mikrobiologia, 44(3-4), 173-85.
Gut W. [Changes in the Level of Humoral Response for Measles Virus in Patients With Subacute Sclerotic Panencephalitis During 1984-1989]. Med Dosw Mikrobiol. 1992;44(3-4):173-85. PubMed PMID: 1305922.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Changes in the level of humoral response for measles virus in patients with subacute sclerotic panencephalitis during 1984-1989]. A1 - Gut,W, PY - 1992/1/1/pubmed PY - 1992/1/1/medline PY - 1992/1/1/entrez SP - 173 EP - 85 JF - Medycyna doswiadczalna i mikrobiologia JO - Med Dosw Mikrobiol VL - 44 IS - 3-4 N2 - Immunological response to measles virus in serum and cerebro-spinal fluid of 338 patients with subacute sclerotic panencephalitis (SSPE) during the years 1984-1989, was investigated. It was found that mean titer and distribution of results of antibody determination by the hemagglutination inhibition (OZHA) method in patients sera are visibly differing during consecutive years of investigation. Analysis of these parameters in determination by the immunoenzymatic methods (ELISA) has shown their higher stability. Also results of determinations of IgG concentration in sera of patients with SSPE did not demonstrate significant differences between consecutive years of investigation. Systematic decrease of mutual relation between antibodies to measles virus detected by ELISA and OZHA was found. Analysis of local synthesis of antibodies to measles virus in the central nervous system has revealed that it most strongly expressed by hemagglutinin. SN - 0025-8601 UR - https://www.unboundmedicine.com/medline/citation/1305922/[Changes_in_the_level_of_humoral_response_for_measles_virus_in_patients_with_subacute_sclerotic_panencephalitis_during_1984_1989]_ DB - PRIME DP - Unbound Medicine ER -