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Intradermal simulated rabies postexposure prophylaxis using purified chick embryo rabies vaccine.
J Med Assoc Thai. 1992 Nov; 75(11):639-43.JM

Abstract

The antibody responses of 65 volunteers receiving an i.d. regimen (0.1 ml given at two different sites on days 0, 3, 7 and 0.1 ml given at one site on days 30 and 90) were compared with a control group of 35 volunteers receiving the standard i.m. regimen. By day 14, seroconversion was observed in all vaccinees in both groups. Geometric mean titers remained higher than 0.5 IU/ml throughout the study period. At the end of the observation period on day 365, antibodies persisted in all subjects. The multisite i.d. PCEC regimen has been proved as immunogenic as the standard i.m. regimen. Both regimens were well tolerated. Thus, it would be the effective and cheapest available rabies postexposure treatment using tissue culture vaccine.

Authors+Show Affiliations

Department of Communicable Disease Control, Ministry of Public Health, Bangkok.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Comparative Study
Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

1307387

Citation

Charanasri, U, et al. "Intradermal Simulated Rabies Postexposure Prophylaxis Using Purified Chick Embryo Rabies Vaccine." Journal of the Medical Association of Thailand = Chotmaihet Thangphaet, vol. 75, no. 11, 1992, pp. 639-43.
Charanasri U, Meesomboon V, Kingnate D, et al. Intradermal simulated rabies postexposure prophylaxis using purified chick embryo rabies vaccine. J Med Assoc Thai. 1992;75(11):639-43.
Charanasri, U., Meesomboon, V., Kingnate, D., Samuthananon, P., & Chaeychomsri, W. (1992). Intradermal simulated rabies postexposure prophylaxis using purified chick embryo rabies vaccine. Journal of the Medical Association of Thailand = Chotmaihet Thangphaet, 75(11), 639-43.
Charanasri U, et al. Intradermal Simulated Rabies Postexposure Prophylaxis Using Purified Chick Embryo Rabies Vaccine. J Med Assoc Thai. 1992;75(11):639-43. PubMed PMID: 1307387.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Intradermal simulated rabies postexposure prophylaxis using purified chick embryo rabies vaccine. AU - Charanasri,U, AU - Meesomboon,V, AU - Kingnate,D, AU - Samuthananon,P, AU - Chaeychomsri,W, PY - 1992/11/1/pubmed PY - 1992/11/1/medline PY - 1992/11/1/entrez SP - 639 EP - 43 JF - Journal of the Medical Association of Thailand = Chotmaihet thangphaet JO - J Med Assoc Thai VL - 75 IS - 11 N2 - The antibody responses of 65 volunteers receiving an i.d. regimen (0.1 ml given at two different sites on days 0, 3, 7 and 0.1 ml given at one site on days 30 and 90) were compared with a control group of 35 volunteers receiving the standard i.m. regimen. By day 14, seroconversion was observed in all vaccinees in both groups. Geometric mean titers remained higher than 0.5 IU/ml throughout the study period. At the end of the observation period on day 365, antibodies persisted in all subjects. The multisite i.d. PCEC regimen has been proved as immunogenic as the standard i.m. regimen. Both regimens were well tolerated. Thus, it would be the effective and cheapest available rabies postexposure treatment using tissue culture vaccine. SN - 0125-2208 UR - https://www.unboundmedicine.com/medline/citation/1307387/Intradermal_simulated_rabies_postexposure_prophylaxis_using_purified_chick_embryo_rabies_vaccine_ L2 - http://www.diseaseinfosearch.org/result/6131 DB - PRIME DP - Unbound Medicine ER -