Tags

Type your tag names separated by a space and hit enter

Role of microorganisms in dandruff.
Arch Dermatol. 1976 Mar; 112(3):333-8.AD

Abstract

The role of microorganisms in dandruff was studied, by suppressing individually and then collectively the three major components of the scalp microflora. The effect on dandruff was assessed subjectively by clinical grading and objectively by the corneocyte count. No effect on dandruff was demonstrated when scalp organisms were suppressed. In the second group of experiments, dandruff was suppressed by selenium sulfide shampooling and the effect of continued suppression of Pityrosporum with topically applied amphotericin was measured. According to our criteria, dandruff returned to pretreatment levels, despite continued suppression of Pityrosporum. The studies demonstrate that the increased number of scalp microorganisms found in dandruff occurs as a secondary event to increased nutrients and that scalp organisms play no primary role in the pathogenesis of dandruff.

Links

Publisher Full Text

Authors

Leyden JJ
No affiliation info available
McGinley KJ
No affiliation info available
Kligman AM
No affiliation info available

MeSH

Amphotericin BClinical Trials as TopicDemeclocyclineDermatitis, SeborrheicHumansMalasseziaNeomycinPropionibacterium acnesScalpScalp DermatosesSeleniumSulfides

Pub Type(s)

Clinical Trial
Controlled Clinical Trial
Journal Article

Language

eng

PubMed ID

130835

Citation

Leyden, J J., et al. "Role of Microorganisms in Dandruff." Archives of Dermatology, vol. 112, no. 3, 1976, pp. 333-8.
Leyden JJ, McGinley KJ, Kligman AM. Role of microorganisms in dandruff. Arch Dermatol. 1976;112(3):333-8.
Leyden, J. J., McGinley, K. J., & Kligman, A. M. (1976). Role of microorganisms in dandruff. Archives of Dermatology, 112(3), 333-8.
Leyden JJ, McGinley KJ, Kligman AM. Role of Microorganisms in Dandruff. Arch Dermatol. 1976;112(3):333-8. PubMed PMID: 130835.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Role of microorganisms in dandruff. AU - Leyden,J J, AU - McGinley,K J, AU - Kligman,A M, PY - 1976/3/1/pubmed PY - 1976/3/1/medline PY - 1976/3/1/entrez SP - 333 EP - 8 JF - Archives of dermatology JO - Arch Dermatol VL - 112 IS - 3 N2 - The role of microorganisms in dandruff was studied, by suppressing individually and then collectively the three major components of the scalp microflora. The effect on dandruff was assessed subjectively by clinical grading and objectively by the corneocyte count. No effect on dandruff was demonstrated when scalp organisms were suppressed. In the second group of experiments, dandruff was suppressed by selenium sulfide shampooling and the effect of continued suppression of Pityrosporum with topically applied amphotericin was measured. According to our criteria, dandruff returned to pretreatment levels, despite continued suppression of Pityrosporum. The studies demonstrate that the increased number of scalp microorganisms found in dandruff occurs as a secondary event to increased nutrients and that scalp organisms play no primary role in the pathogenesis of dandruff. SN - 0003-987X UR - https://www.unboundmedicine.com/medline/citation/130835/Role_of_microorganisms_in_dandruff_ L2 - https://jamanetwork.com/journals/jamadermatology/fullarticle/vol/112/pg/333 DB - PRIME DP - Unbound Medicine ER -