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Isocitrate dehydrogenase kinase/phosphatase: identification of mutations which selectively inhibit phosphatase activity.
J Bacteriol. 1992 Feb; 174(4):1414-6.JB

Abstract

Mutations in aceK, the gene encoding isocitrate dehydrogenase kinase/phosphatase, which selectively inhibit phosphatase activity have been isolated. These mutations yield amino acid substitutions within a 113-residue region of this 578-residue protein. These mutations may define a regulatory domain of this protein.

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Authors+Show Affiliations

Ikeda TP
Department of Biochemistry, University of Minnesota, Minneapolis 55455-0347.
Houtz E
No affiliation info available
LaPorte DC
No affiliation info available

MeSH

DNA Mutational AnalysisEscherichia coliMutationPhosphoprotein PhosphatasesProtein KinasesProtein Serine-Threonine KinasesTransformation, Bacterial

Pub Type(s)

Journal Article
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

1310504

Citation

Ikeda, T P., et al. "Isocitrate Dehydrogenase Kinase/phosphatase: Identification of Mutations Which Selectively Inhibit Phosphatase Activity." Journal of Bacteriology, vol. 174, no. 4, 1992, pp. 1414-6.
Ikeda TP, Houtz E, LaPorte DC. Isocitrate dehydrogenase kinase/phosphatase: identification of mutations which selectively inhibit phosphatase activity. J Bacteriol. 1992;174(4):1414-6.
Ikeda, T. P., Houtz, E., & LaPorte, D. C. (1992). Isocitrate dehydrogenase kinase/phosphatase: identification of mutations which selectively inhibit phosphatase activity. Journal of Bacteriology, 174(4), 1414-6.
Ikeda TP, Houtz E, LaPorte DC. Isocitrate Dehydrogenase Kinase/phosphatase: Identification of Mutations Which Selectively Inhibit Phosphatase Activity. J Bacteriol. 1992;174(4):1414-6. PubMed PMID: 1310504.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Isocitrate dehydrogenase kinase/phosphatase: identification of mutations which selectively inhibit phosphatase activity. AU - Ikeda,T P, AU - Houtz,E, AU - LaPorte,D C, PY - 1992/2/1/pubmed PY - 1992/2/1/medline PY - 1992/2/1/entrez SP - 1414 EP - 6 JF - Journal of bacteriology JO - J Bacteriol VL - 174 IS - 4 N2 - Mutations in aceK, the gene encoding isocitrate dehydrogenase kinase/phosphatase, which selectively inhibit phosphatase activity have been isolated. These mutations yield amino acid substitutions within a 113-residue region of this 578-residue protein. These mutations may define a regulatory domain of this protein. SN - 0021-9193 UR - https://www.unboundmedicine.com/medline/citation/1310504/Isocitrate_dehydrogenase_kinase/phosphatase:_identification_of_mutations_which_selectively_inhibit_phosphatase_activity_ DB - PRIME DP - Unbound Medicine ER -