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Fine needle aspiration cytology of phyllodes tumor. Potential diagnostic pitfalls.
Acta Cytol. 1992 Mar-Apr; 36(2):215-21.AC

Abstract

We reviewed the fine needle aspiration cytologic findings in six cases of phyllodes tumor (PT). The average age of the patients at the time of the diagnosis was 47 years. Two cases were correctly diagnosed cytologically; both were malignant histologically. Of the histologically benign tumors, two were misdiagnosed as carcinoma, and a third was considered suspicious for carcinoma. The remaining case was diagnosed descriptively as "benign duct epithelium." Possible reasons for overdiagnosis include high cellularity of the smears, the presence of atypical ductal hyperplasia, paucity of the stromal component in the aspirates and occasional dissociation of epithelial cells. Recommendations are offered to prevent misdiagnosis. The cytologic differential diagnosis between fibroadenoma and PT is discussed briefly, and the considerable cytologic overlap that can occur is emphasized. The specific cytologic diagnosis of PT is not possible in many cases, but the presence of certain cytologic features in the correct clinical setting allows the diagnosis to be suggested.

Authors+Show Affiliations

Dusenbery D
Department of Pathology, Medical College of Virginia/Virginia Commonwealth University, Richmond 23298-0115.
Frable WJ
No affiliation info available

MeSH

AdultBiopsy, NeedleBreast NeoplasmsCarcinomaDiagnosis, DifferentialFemaleHumansMiddle AgedPhyllodes TumorRetrospective Studies

Pub Type(s)

Journal Article

Language

eng

PubMed ID

1311889

Citation

Dusenbery, D, and W J. Frable. "Fine Needle Aspiration Cytology of Phyllodes Tumor. Potential Diagnostic Pitfalls." Acta Cytologica, vol. 36, no. 2, 1992, pp. 215-21.
Dusenbery D, Frable WJ. Fine needle aspiration cytology of phyllodes tumor. Potential diagnostic pitfalls. Acta Cytol. 1992;36(2):215-21.
Dusenbery, D., & Frable, W. J. (1992). Fine needle aspiration cytology of phyllodes tumor. Potential diagnostic pitfalls. Acta Cytologica, 36(2), 215-21.
Dusenbery D, Frable WJ. Fine Needle Aspiration Cytology of Phyllodes Tumor. Potential Diagnostic Pitfalls. Acta Cytol. 1992 Mar-Apr;36(2):215-21. PubMed PMID: 1311889.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Fine needle aspiration cytology of phyllodes tumor. Potential diagnostic pitfalls. AU - Dusenbery,D, AU - Frable,W J, PY - 1992/3/1/pubmed PY - 1992/3/1/medline PY - 1992/3/1/entrez SP - 215 EP - 21 JF - Acta cytologica JO - Acta Cytol VL - 36 IS - 2 N2 - We reviewed the fine needle aspiration cytologic findings in six cases of phyllodes tumor (PT). The average age of the patients at the time of the diagnosis was 47 years. Two cases were correctly diagnosed cytologically; both were malignant histologically. Of the histologically benign tumors, two were misdiagnosed as carcinoma, and a third was considered suspicious for carcinoma. The remaining case was diagnosed descriptively as "benign duct epithelium." Possible reasons for overdiagnosis include high cellularity of the smears, the presence of atypical ductal hyperplasia, paucity of the stromal component in the aspirates and occasional dissociation of epithelial cells. Recommendations are offered to prevent misdiagnosis. The cytologic differential diagnosis between fibroadenoma and PT is discussed briefly, and the considerable cytologic overlap that can occur is emphasized. The specific cytologic diagnosis of PT is not possible in many cases, but the presence of certain cytologic features in the correct clinical setting allows the diagnosis to be suggested. SN - 0001-5547 UR - https://www.unboundmedicine.com/medline/citation/1311889/Fine_needle_aspiration_cytology_of_phyllodes_tumor__Potential_diagnostic_pitfalls_ L2 - http://www.diseaseinfosearch.org/result/2083 DB - PRIME DP - Unbound Medicine ER -