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Oat bran lowers plasma cholesterol levels in mildly hypercholesterolemic men.
J Am Diet Assoc. 1992 Apr; 92(4):446-9.JA

Abstract

The effects of oat bran and wheat bran on plasma lipid concentrations were compared in a crossover study. Each bran (123 g oat bran or 54 g wheat bran) added nearly 18 g of nonstarch polysaccharide to a background diet containing about 10 g nonstarch polysaccharide. Twenty-three men (average plasma cholesterol level = 5.84 mmol/L, and low-density-lipoprotein (LDL) cholesterol level = 4.11 mmol/L) were randomly assigned to either the oat or wheat bran diet for 4 weeks and then changed to the alternate bran diet for a similar period. The oat bran diet produced significantly lower levels of plasma total cholesterol and LDL cholesterol: 5.65 +/- 0.16 and 3.88 +/- 0.15 mmol/L (mean +/- standard error) for oat bran vs 5.89 +/- 0.16 and 4.11 +/- 0.16 mmol/L for wheat bran. Food intake diaries showed that average consumption of total fat and saturated fat was identical during the two test periods, which excluded displacement of fat as an explanation for lowering of plasma cholesterol by oat bran. Our results indicate that in mildly hypercholesterolemic men, a diet high in soluble oat fiber can significantly lower plasma total cholesterol and LDL cholesterol and thus potentially lower the risk of coronary heart disease.

Authors+Show Affiliations

Department of Nutrition, School of Public Health, University of North Carolina.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Comparative Study
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

1313467

Citation

Whyte, J L., et al. "Oat Bran Lowers Plasma Cholesterol Levels in Mildly Hypercholesterolemic Men." Journal of the American Dietetic Association, vol. 92, no. 4, 1992, pp. 446-9.
Whyte JL, McArthur R, Topping D, et al. Oat bran lowers plasma cholesterol levels in mildly hypercholesterolemic men. J Am Diet Assoc. 1992;92(4):446-9.
Whyte, J. L., McArthur, R., Topping, D., & Nestel, P. (1992). Oat bran lowers plasma cholesterol levels in mildly hypercholesterolemic men. Journal of the American Dietetic Association, 92(4), 446-9.
Whyte JL, et al. Oat Bran Lowers Plasma Cholesterol Levels in Mildly Hypercholesterolemic Men. J Am Diet Assoc. 1992;92(4):446-9. PubMed PMID: 1313467.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Oat bran lowers plasma cholesterol levels in mildly hypercholesterolemic men. AU - Whyte,J L, AU - McArthur,R, AU - Topping,D, AU - Nestel,P, PY - 1992/4/1/pubmed PY - 1992/4/1/medline PY - 1992/4/1/entrez SP - 446 EP - 9 JF - Journal of the American Dietetic Association JO - J Am Diet Assoc VL - 92 IS - 4 N2 - The effects of oat bran and wheat bran on plasma lipid concentrations were compared in a crossover study. Each bran (123 g oat bran or 54 g wheat bran) added nearly 18 g of nonstarch polysaccharide to a background diet containing about 10 g nonstarch polysaccharide. Twenty-three men (average plasma cholesterol level = 5.84 mmol/L, and low-density-lipoprotein (LDL) cholesterol level = 4.11 mmol/L) were randomly assigned to either the oat or wheat bran diet for 4 weeks and then changed to the alternate bran diet for a similar period. The oat bran diet produced significantly lower levels of plasma total cholesterol and LDL cholesterol: 5.65 +/- 0.16 and 3.88 +/- 0.15 mmol/L (mean +/- standard error) for oat bran vs 5.89 +/- 0.16 and 4.11 +/- 0.16 mmol/L for wheat bran. Food intake diaries showed that average consumption of total fat and saturated fat was identical during the two test periods, which excluded displacement of fat as an explanation for lowering of plasma cholesterol by oat bran. Our results indicate that in mildly hypercholesterolemic men, a diet high in soluble oat fiber can significantly lower plasma total cholesterol and LDL cholesterol and thus potentially lower the risk of coronary heart disease. SN - 0002-8223 UR - https://www.unboundmedicine.com/medline/citation/1313467/Oat_bran_lowers_plasma_cholesterol_levels_in_mildly_hypercholesterolemic_men_ L2 - https://medlineplus.gov/cholesterollevelswhatyouneedtoknow.html DB - PRIME DP - Unbound Medicine ER -