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Intolerance to sodium metabisulfite in children with steroid-dependent asthma.
J Investig Allergol Clin Immunol 1992 Jan-Feb; 2(1):36-8JI

Abstract

Oral challenge tests were carried out with sodium metabisulfite solution doses of 5, 10, 25, 50 and 100 mg, dissolved in 20 ml of citric acid, and administered to 20 children aged 7-14 years with steroid-dependent bronchial asthma. A single-blind challenge protocol was performed initially and the positive responses were confirmed by double-blind challenge. Initially, 6 of 20 presented a positive reaction, confirmed in 4 of 20 by double-blind challenge. Only 1 child was clinically suspected of exhibiting intolerance to this agent. The prevalence of the challenge test using sodium metabisulfite in children with steroid-dependent bronchial asthma was 20%.

Authors+Show Affiliations

Pediatrics Department, Valencia University, Spain.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

1342881

Citation

Sanz, J, et al. "Intolerance to Sodium Metabisulfite in Children With Steroid-dependent Asthma." Journal of Investigational Allergology & Clinical Immunology, vol. 2, no. 1, 1992, pp. 36-8.
Sanz J, Martorell A, Torro I, et al. Intolerance to sodium metabisulfite in children with steroid-dependent asthma. J Investig Allergol Clin Immunol. 1992;2(1):36-8.
Sanz, J., Martorell, A., Torro, I., Carlos Cerda, J., & Alvarez, V. (1992). Intolerance to sodium metabisulfite in children with steroid-dependent asthma. Journal of Investigational Allergology & Clinical Immunology, 2(1), pp. 36-8.
Sanz J, et al. Intolerance to Sodium Metabisulfite in Children With Steroid-dependent Asthma. J Investig Allergol Clin Immunol. 1992;2(1):36-8. PubMed PMID: 1342881.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Intolerance to sodium metabisulfite in children with steroid-dependent asthma. AU - Sanz,J, AU - Martorell,A, AU - Torro,I, AU - Carlos Cerda,J, AU - Alvarez,V, PY - 1992/1/1/pubmed PY - 1992/1/1/medline PY - 1992/1/1/entrez SP - 36 EP - 8 JF - Journal of investigational allergology & clinical immunology JO - J Investig Allergol Clin Immunol VL - 2 IS - 1 N2 - Oral challenge tests were carried out with sodium metabisulfite solution doses of 5, 10, 25, 50 and 100 mg, dissolved in 20 ml of citric acid, and administered to 20 children aged 7-14 years with steroid-dependent bronchial asthma. A single-blind challenge protocol was performed initially and the positive responses were confirmed by double-blind challenge. Initially, 6 of 20 presented a positive reaction, confirmed in 4 of 20 by double-blind challenge. Only 1 child was clinically suspected of exhibiting intolerance to this agent. The prevalence of the challenge test using sodium metabisulfite in children with steroid-dependent bronchial asthma was 20%. SN - 1018-9068 UR - https://www.unboundmedicine.com/medline/citation/1342881/Intolerance_to_sodium_metabisulfite_in_children_with_steroid_dependent_asthma_ L2 - http://www.diseaseinfosearch.org/result/633 DB - PRIME DP - Unbound Medicine ER -