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A FIELD trial of freeze-dried glutamate BCG vaccine; preliminary report.
Bull World Health Organ 1957; 17(2):289-93BW

Abstract

A field trial of dried BCG vaccine prepared with sodium glutamate as adjuvant was carried out by the WHO/UNICEF Tuberculosis Survey Team for West Africa in Ilorin, Nigeria, in April 1956. This trial-the first of a series of studies being undertaken jointly by the WHO Tuberculosis Research Office and the Japan Anti-Tuberculosis Association-was designed to test the heat-stability of the new dried vaccine.The allergenic potency six months after vaccination of two different lots of glutamate vaccine stored under various temperature conditions was compared with that of a batch of fresh liquid vaccine stored at 2-4 degrees C. The results showed both lots of dried vaccine to be remarkably heat-stable: even after 30 days' exposure to tropical temperatures, no marked loss of allergenic potency was observed.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

13489469

Citation

"A FIELD Trial of Freeze-dried Glutamate BCG Vaccine; Preliminary Report." Bulletin of the World Health Organization, vol. 17, no. 2, 1957, pp. 289-93.
A FIELD trial of freeze-dried glutamate BCG vaccine; preliminary report. Bull World Health Organ. 1957;17(2):289-93.
(1957). A FIELD trial of freeze-dried glutamate BCG vaccine; preliminary report. Bulletin of the World Health Organization, 17(2), pp. 289-93.
A FIELD Trial of Freeze-dried Glutamate BCG Vaccine; Preliminary Report. Bull World Health Organ. 1957;17(2):289-93. PubMed PMID: 13489469.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A FIELD trial of freeze-dried glutamate BCG vaccine; preliminary report. PY - 1957/1/1/pubmed PY - 1957/1/1/medline PY - 1957/1/1/entrez KW - BCG VACCINATION SP - 289 EP - 93 JF - Bulletin of the World Health Organization JO - Bull. World Health Organ. VL - 17 IS - 2 N2 - A field trial of dried BCG vaccine prepared with sodium glutamate as adjuvant was carried out by the WHO/UNICEF Tuberculosis Survey Team for West Africa in Ilorin, Nigeria, in April 1956. This trial-the first of a series of studies being undertaken jointly by the WHO Tuberculosis Research Office and the Japan Anti-Tuberculosis Association-was designed to test the heat-stability of the new dried vaccine.The allergenic potency six months after vaccination of two different lots of glutamate vaccine stored under various temperature conditions was compared with that of a batch of fresh liquid vaccine stored at 2-4 degrees C. The results showed both lots of dried vaccine to be remarkably heat-stable: even after 30 days' exposure to tropical temperatures, no marked loss of allergenic potency was observed. SN - 0042-9686 UR - https://www.unboundmedicine.com/medline/citation/13489469/A_FIELD_trial_of_freeze_dried_glutamate_BCG_vaccine L2 - https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/13489469/ DB - PRIME DP - Unbound Medicine ER -