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Combined sclerotherapy and operation for the treatment of bleeding oesophageal varices.
Eur J Surg. 1992 Sep; 158(9):485-9.EJ

Abstract

OBJECTIVE

To identify prognostic factors in a consecutive series of patients with bleeding oesophageal varices and develop an optimum regimen of treatment.

DESIGN

Retrospective review.

SETTING

I Department of Surgery, University Hospital, Vienna, Austria.

PATIENTS

301 consecutive patients with bleeding oesophageal varices.

OUTCOME MEASURES

Median survival and survival at one year after sclerotherapy alone (n = 213), or sclerotherapy with portosystemic shunt (n = 54), Hassab's devascularisation (n = 29), or liver transplantation (n = 5).

RESULTS

Prognosis was dependent on the severity of liver damage at the start of treatment. Median survival for Child's class A was 47 months, for Child's class B 54 months, and for Child's class C 2 months. The overall one year survival for patients in Child's class C was 33%, for sclerotherapy alone 28%, and for sclerotherapy and portosystemic shunt 42%, Hassab's devascularisation 50%, and liver transplantation 80%.

CONCLUSION

Despite the small number of patients who underwent liver transplantation and their poor initial prognosis (Child's class C, n = 4; class B, n = 1) our results suggest that liver transplantation should be considered for the treatment of patients with end stage cirrhosis and bleeding varices.

Authors+Show Affiliations

I. Chirurgische Universitätsklinik, University of Vienna, Austria.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

1358216

Citation

Függer, R, et al. "Combined Sclerotherapy and Operation for the Treatment of Bleeding Oesophageal Varices." The European Journal of Surgery = Acta Chirurgica, vol. 158, no. 9, 1992, pp. 485-9.
Függer R, Herbst F, Mirza D, et al. Combined sclerotherapy and operation for the treatment of bleeding oesophageal varices. Eur J Surg. 1992;158(9):485-9.
Függer, R., Herbst, F., Mirza, D., Rogy, M., Steininger, R., & Schulz, F. (1992). Combined sclerotherapy and operation for the treatment of bleeding oesophageal varices. The European Journal of Surgery = Acta Chirurgica, 158(9), 485-9.
Függer R, et al. Combined Sclerotherapy and Operation for the Treatment of Bleeding Oesophageal Varices. Eur J Surg. 1992;158(9):485-9. PubMed PMID: 1358216.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Combined sclerotherapy and operation for the treatment of bleeding oesophageal varices. AU - Függer,R, AU - Herbst,F, AU - Mirza,D, AU - Rogy,M, AU - Steininger,R, AU - Schulz,F, PY - 1992/9/1/pubmed PY - 1992/9/1/medline PY - 1992/9/1/entrez SP - 485 EP - 9 JF - The European journal of surgery = Acta chirurgica JO - Eur J Surg VL - 158 IS - 9 N2 - OBJECTIVE: To identify prognostic factors in a consecutive series of patients with bleeding oesophageal varices and develop an optimum regimen of treatment. DESIGN: Retrospective review. SETTING: I Department of Surgery, University Hospital, Vienna, Austria. PATIENTS: 301 consecutive patients with bleeding oesophageal varices. OUTCOME MEASURES: Median survival and survival at one year after sclerotherapy alone (n = 213), or sclerotherapy with portosystemic shunt (n = 54), Hassab's devascularisation (n = 29), or liver transplantation (n = 5). RESULTS: Prognosis was dependent on the severity of liver damage at the start of treatment. Median survival for Child's class A was 47 months, for Child's class B 54 months, and for Child's class C 2 months. The overall one year survival for patients in Child's class C was 33%, for sclerotherapy alone 28%, and for sclerotherapy and portosystemic shunt 42%, Hassab's devascularisation 50%, and liver transplantation 80%. CONCLUSION: Despite the small number of patients who underwent liver transplantation and their poor initial prognosis (Child's class C, n = 4; class B, n = 1) our results suggest that liver transplantation should be considered for the treatment of patients with end stage cirrhosis and bleeding varices. SN - 1102-4151 UR - https://www.unboundmedicine.com/medline/citation/1358216/Combined_sclerotherapy_and_operation_for_the_treatment_of_bleeding_oesophageal_varices_ L2 - https://medlineplus.gov/gastrointestinalbleeding.html DB - PRIME DP - Unbound Medicine ER -