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Some features of Cannabis plants grown in the United Kingdom from seeds of known origin.

Abstract

The cannabinoid content of UK-grown plants (up to the 6th generation) from Moroccan, Sri Lankan and Zambian seedstock was determined by TLC, GLC and HPLC. All plants from the 5th and 6th series resembled their parents, and UK-grown plants were always much greener than those grown overseas. Cannabinoid content remained broadly typical of the source countries. However, tetrahydrocannabinolic acid (THCA) consistently predominated over tetrahydrocannabinol (THC) to a far greater extent than in the original plants; the THCA/THC ratio was 17 in UK-grown plants compared with 2.0 in the plants from the original areas. Two types of plant emerged from the Moroccan seedstock, one tending to increased cannabidiol (CBD), the other tending to zero levels of this component. The first generation Sri Lankan plants revealed one type of plant with an increased CBD/THC ratio (1.7 compared with 0.11) but this returned to the original value in the succeeding generations. Other Sri Lankan plants had low or undetectable levels of CBD. Moroccan and Sri Lankan CBD-rich plants did not contain cannabichromene, although this cannabinoid was found in THC-rich plants. Zambian plants did not appear to show such a pattern. Zambian seedstock plants had total tetrahydrocannabivarin (diol and acid) levels greater than THC but the ratio was progressively reversed in succeeding generations. The study concludes that the ratios of particular cannabinoids is greatly influenced by the environment.

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  • Publisher Full Text
  • Authors+Show Affiliations

    ,

    Laboratory of the Government Chemist, Teddington, UK.

    ,

    Source

    MeSH

    Cannabinoids
    Cannabis
    Morocco
    Seeds
    Sri Lanka
    Zambia

    Pub Type(s)

    Comparative Study
    Journal Article

    Language

    eng

    PubMed ID

    1361557

    Citation

    Pitts, J E., et al. "Some Features of Cannabis Plants Grown in the United Kingdom From Seeds of Known Origin." The Journal of Pharmacy and Pharmacology, vol. 44, no. 12, 1992, pp. 947-51.
    Pitts JE, Neal JD, Gough TA. Some features of Cannabis plants grown in the United Kingdom from seeds of known origin. J Pharm Pharmacol. 1992;44(12):947-51.
    Pitts, J. E., Neal, J. D., & Gough, T. A. (1992). Some features of Cannabis plants grown in the United Kingdom from seeds of known origin. The Journal of Pharmacy and Pharmacology, 44(12), pp. 947-51.
    Pitts JE, Neal JD, Gough TA. Some Features of Cannabis Plants Grown in the United Kingdom From Seeds of Known Origin. J Pharm Pharmacol. 1992;44(12):947-51. PubMed PMID: 1361557.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Some features of Cannabis plants grown in the United Kingdom from seeds of known origin. AU - Pitts,J E, AU - Neal,J D, AU - Gough,T A, PY - 1992/12/1/pubmed PY - 1992/12/1/medline PY - 1992/12/1/entrez SP - 947 EP - 51 JF - The Journal of pharmacy and pharmacology JO - J. Pharm. Pharmacol. VL - 44 IS - 12 N2 - The cannabinoid content of UK-grown plants (up to the 6th generation) from Moroccan, Sri Lankan and Zambian seedstock was determined by TLC, GLC and HPLC. All plants from the 5th and 6th series resembled their parents, and UK-grown plants were always much greener than those grown overseas. Cannabinoid content remained broadly typical of the source countries. However, tetrahydrocannabinolic acid (THCA) consistently predominated over tetrahydrocannabinol (THC) to a far greater extent than in the original plants; the THCA/THC ratio was 17 in UK-grown plants compared with 2.0 in the plants from the original areas. Two types of plant emerged from the Moroccan seedstock, one tending to increased cannabidiol (CBD), the other tending to zero levels of this component. The first generation Sri Lankan plants revealed one type of plant with an increased CBD/THC ratio (1.7 compared with 0.11) but this returned to the original value in the succeeding generations. Other Sri Lankan plants had low or undetectable levels of CBD. Moroccan and Sri Lankan CBD-rich plants did not contain cannabichromene, although this cannabinoid was found in THC-rich plants. Zambian plants did not appear to show such a pattern. Zambian seedstock plants had total tetrahydrocannabivarin (diol and acid) levels greater than THC but the ratio was progressively reversed in succeeding generations. The study concludes that the ratios of particular cannabinoids is greatly influenced by the environment. SN - 0022-3573 UR - https://www.unboundmedicine.com/medline/citation/1361557/abstract/ L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0022-3573&date=1992&volume=44&issue=12&spage=947 DB - PRIME DP - Unbound Medicine ER -