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CAPD in end stage patients with renal disease due to diabetes mellitus--an update.
Adv Perit Dial. 1992; 8:185-91.AP

Abstract

Large numbers of diabetics with renal failure have been treated by continuous ambulatory peritoneal dialysis (CAPD). Overall 1-year patient survival varies from 51% to 87%. Mortality is due to cardiovascular disease in more than 50% of the cases. Young diabetics with good blood pressure control and without cardiac disease have a chance at long survival on CAPD. In comparison to hemodialysis, CAPD yields better patient survival for young diabetics and worse for old diabetics, worse technique survival, probably greater overall morbidity, and similar rates of progression of retinopathy, neuropathy and peripheral vascular disease. Adequacy of peritoneal clearance and peritoneal ultrafiltration characteristics are similar between diabetics and non-diabetics on CAPD. CAPD is associated with better preservation of renal function than hemodialysis in diabetics. The rates of CAPD peritonitis do not differ substantially between diabetics and non-diabetics. However, diabetes appears to be associated with higher incidence of tunnel infection. Hyperlipidemia is generally less severe in diabetics than non-diabetics on CAPD, but malnutrition is more frequent in diabetics. CAPD has many attractive features and several drawbacks for the management of diabetics with end stage renal failure (ESRF). Its ultimate success will depend on the outcome of efforts to improve cardiovascular mortality, malnutrition, hyperlipidemia and catheter-related infections.

Authors+Show Affiliations

Renal Section, VA Medical Center, Albuquerque, NM 87108.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

1361783

Citation

Tzamaloukas, A H., et al. "CAPD in End Stage Patients With Renal Disease Due to Diabetes Mellitus--an Update." Advances in Peritoneal Dialysis. Conference On Peritoneal Dialysis, vol. 8, 1992, pp. 185-91.
Tzamaloukas AH, Yuan ZY, Balaskas E, et al. CAPD in end stage patients with renal disease due to diabetes mellitus--an update. Adv Perit Dial. 1992;8:185-91.
Tzamaloukas, A. H., Yuan, Z. Y., Balaskas, E., & Oreopoulos, D. G. (1992). CAPD in end stage patients with renal disease due to diabetes mellitus--an update. Advances in Peritoneal Dialysis. Conference On Peritoneal Dialysis, 8, 185-91.
Tzamaloukas AH, et al. CAPD in End Stage Patients With Renal Disease Due to Diabetes Mellitus--an Update. Adv Perit Dial. 1992;8:185-91. PubMed PMID: 1361783.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - CAPD in end stage patients with renal disease due to diabetes mellitus--an update. AU - Tzamaloukas,A H, AU - Yuan,Z Y, AU - Balaskas,E, AU - Oreopoulos,D G, PY - 1992/1/1/pubmed PY - 1992/1/1/medline PY - 1992/1/1/entrez SP - 185 EP - 91 JF - Advances in peritoneal dialysis. Conference on Peritoneal Dialysis JO - Adv Perit Dial VL - 8 N2 - Large numbers of diabetics with renal failure have been treated by continuous ambulatory peritoneal dialysis (CAPD). Overall 1-year patient survival varies from 51% to 87%. Mortality is due to cardiovascular disease in more than 50% of the cases. Young diabetics with good blood pressure control and without cardiac disease have a chance at long survival on CAPD. In comparison to hemodialysis, CAPD yields better patient survival for young diabetics and worse for old diabetics, worse technique survival, probably greater overall morbidity, and similar rates of progression of retinopathy, neuropathy and peripheral vascular disease. Adequacy of peritoneal clearance and peritoneal ultrafiltration characteristics are similar between diabetics and non-diabetics on CAPD. CAPD is associated with better preservation of renal function than hemodialysis in diabetics. The rates of CAPD peritonitis do not differ substantially between diabetics and non-diabetics. However, diabetes appears to be associated with higher incidence of tunnel infection. Hyperlipidemia is generally less severe in diabetics than non-diabetics on CAPD, but malnutrition is more frequent in diabetics. CAPD has many attractive features and several drawbacks for the management of diabetics with end stage renal failure (ESRF). Its ultimate success will depend on the outcome of efforts to improve cardiovascular mortality, malnutrition, hyperlipidemia and catheter-related infections. SN - 1197-8554 UR - https://www.unboundmedicine.com/medline/citation/1361783/CAPD_in_end_stage_patients_with_renal_disease_due_to_diabetes_mellitus__an_update_ L2 - http://www.diseaseinfosearch.org/result/2236 DB - PRIME DP - Unbound Medicine ER -