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Study on the inhibitory effects of Korean medicinal plants and their main compounds on the 1,1-diphenyl-2-picrylhydrazyl radical.
Phytomedicine. 2003; 10(6-7):544-51.P

Abstract

A 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical-generating system was used to evaluate the antioxidant properties of Korean medicinal plants that have been used widely as folk medicines for several disorders, as well as compounds isolated from them. Among the Rosaceae, Rosa rugosa and Rosa davurica showed strong DPPH radical-scavenging activity. The most effective medicinal plant from families other than Rosaceae was Cedrela sinensis, followed in order by Nelumbo nucifera, Eucommia ulmoides, Zanthoxylum piperitum, Cudrania tricuspidata and Houttuynia cordata. These results serve as a good index of the free radical-scavenging activities of Korean medicinal plants. Furthermore, the polyphenols isolated from these plants, procyanidin B-3, (+)-catechin, gallic acid, methyl gallate, quercetin, quercetin-3-O-beta-D-glucoside, quercetin-3-O-beta-galactoside, quercetin-3-O-rutinose and kaempferol, exerted strong DPPH radical-scavenging activity. These results suggest that the Korean medicinal plants and the polyphenols isolated from them that exhibited effective radical-scavenging activity may be promising agents for scavenging free radicals and treating diseases associated with excess free radicals.

Authors+Show Affiliations

Institute of Natural Medicine, Toyama Medical and Pharmaceutical University, Sugitani, Toyama, Japan.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

13678241

Citation

Cho, E J., et al. "Study On the Inhibitory Effects of Korean Medicinal Plants and Their Main Compounds On the 1,1-diphenyl-2-picrylhydrazyl Radical." Phytomedicine : International Journal of Phytotherapy and Phytopharmacology, vol. 10, no. 6-7, 2003, pp. 544-51.
Cho EJ, Yokozawa T, Rhyu DY, et al. Study on the inhibitory effects of Korean medicinal plants and their main compounds on the 1,1-diphenyl-2-picrylhydrazyl radical. Phytomedicine. 2003;10(6-7):544-51.
Cho, E. J., Yokozawa, T., Rhyu, D. Y., Kim, S. C., Shibahara, N., & Park, J. C. (2003). Study on the inhibitory effects of Korean medicinal plants and their main compounds on the 1,1-diphenyl-2-picrylhydrazyl radical. Phytomedicine : International Journal of Phytotherapy and Phytopharmacology, 10(6-7), 544-51.
Cho EJ, et al. Study On the Inhibitory Effects of Korean Medicinal Plants and Their Main Compounds On the 1,1-diphenyl-2-picrylhydrazyl Radical. Phytomedicine. 2003;10(6-7):544-51. PubMed PMID: 13678241.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Study on the inhibitory effects of Korean medicinal plants and their main compounds on the 1,1-diphenyl-2-picrylhydrazyl radical. AU - Cho,E J, AU - Yokozawa,T, AU - Rhyu,D Y, AU - Kim,S C, AU - Shibahara,N, AU - Park,J C, PY - 2003/9/19/pubmed PY - 2004/1/6/medline PY - 2003/9/19/entrez SP - 544 EP - 51 JF - Phytomedicine : international journal of phytotherapy and phytopharmacology JO - Phytomedicine VL - 10 IS - 6-7 N2 - A 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical-generating system was used to evaluate the antioxidant properties of Korean medicinal plants that have been used widely as folk medicines for several disorders, as well as compounds isolated from them. Among the Rosaceae, Rosa rugosa and Rosa davurica showed strong DPPH radical-scavenging activity. The most effective medicinal plant from families other than Rosaceae was Cedrela sinensis, followed in order by Nelumbo nucifera, Eucommia ulmoides, Zanthoxylum piperitum, Cudrania tricuspidata and Houttuynia cordata. These results serve as a good index of the free radical-scavenging activities of Korean medicinal plants. Furthermore, the polyphenols isolated from these plants, procyanidin B-3, (+)-catechin, gallic acid, methyl gallate, quercetin, quercetin-3-O-beta-D-glucoside, quercetin-3-O-beta-galactoside, quercetin-3-O-rutinose and kaempferol, exerted strong DPPH radical-scavenging activity. These results suggest that the Korean medicinal plants and the polyphenols isolated from them that exhibited effective radical-scavenging activity may be promising agents for scavenging free radicals and treating diseases associated with excess free radicals. SN - 0944-7113 UR - https://www.unboundmedicine.com/medline/citation/13678241/Study_on_the_inhibitory_effects_of_Korean_medicinal_plants_and_their_main_compounds_on_the_11_diphenyl_2_picrylhydrazyl_radical_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0944-7113(04)70261-5 DB - PRIME DP - Unbound Medicine ER -