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[A case of giant pigmented nevus with multiple meningiomas].
Rinsho Shinkeigaku. 1992 Apr; 32(4):457-60.RS

Abstract

A 36-year-old female had a giant congenital pigmented nevus on her anterior trunk. She complained of muscle weakness of the right arm and leg in August 1988, and she was admitted to our hospital to take medical examinations in September 1988. Neurological examination revealed right hemiparesis and exaggerated deep tendon reflexes. Three small falx meningiomas were shown on CT scans and MR images, but they did not appear to be causes of her symptoms. CT-myelography and MR images revealed an intradural extramedullary tumor spreading from the foramen magnum to C2. Oncotomy and C1 laminectomy were performed. Histological finding was compatible with transitional meningioma. Neurological symptoms markedly improved after operation. This patient is considered as a case of neurocutaneous syndrome with central nervous system tumors. Considering that both giant pigmented nevus and meningioma originate from neural crest, they appear to be closely related each other. Such a combination of giant pigmented nevus and meningioma has not yet been reported.

Authors+Show Affiliations

Hara M
Department of Neurology, Shizuoka Red Cross Hospital.
Okabe T
No affiliation info available
Inafuku T
No affiliation info available
Hamaguchi K
No affiliation info available
Yamada F
No affiliation info available

MeSH

AdultFemaleHumansMeningeal NeoplasmsMeningiomaNeoplasms, Multiple PrimaryNevus, PigmentedSkin Neoplasms

Pub Type(s)

Case Reports
English Abstract
Journal Article

Language

jpn

PubMed ID

1395338

Citation

Hara, M, et al. "[A Case of Giant Pigmented Nevus With Multiple Meningiomas]." Rinsho Shinkeigaku = Clinical Neurology, vol. 32, no. 4, 1992, pp. 457-60.
Hara M, Okabe T, Inafuku T, et al. [A case of giant pigmented nevus with multiple meningiomas]. Rinsho Shinkeigaku. 1992;32(4):457-60.
Hara, M., Okabe, T., Inafuku, T., Hamaguchi, K., & Yamada, F. (1992). [A case of giant pigmented nevus with multiple meningiomas]. Rinsho Shinkeigaku = Clinical Neurology, 32(4), 457-60.
Hara M, et al. [A Case of Giant Pigmented Nevus With Multiple Meningiomas]. Rinsho Shinkeigaku. 1992;32(4):457-60. PubMed PMID: 1395338.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [A case of giant pigmented nevus with multiple meningiomas]. AU - Hara,M, AU - Okabe,T, AU - Inafuku,T, AU - Hamaguchi,K, AU - Yamada,F, PY - 1992/4/1/pubmed PY - 1992/4/1/medline PY - 1992/4/1/entrez SP - 457 EP - 60 JF - Rinsho shinkeigaku = Clinical neurology JO - Rinsho Shinkeigaku VL - 32 IS - 4 N2 - A 36-year-old female had a giant congenital pigmented nevus on her anterior trunk. She complained of muscle weakness of the right arm and leg in August 1988, and she was admitted to our hospital to take medical examinations in September 1988. Neurological examination revealed right hemiparesis and exaggerated deep tendon reflexes. Three small falx meningiomas were shown on CT scans and MR images, but they did not appear to be causes of her symptoms. CT-myelography and MR images revealed an intradural extramedullary tumor spreading from the foramen magnum to C2. Oncotomy and C1 laminectomy were performed. Histological finding was compatible with transitional meningioma. Neurological symptoms markedly improved after operation. This patient is considered as a case of neurocutaneous syndrome with central nervous system tumors. Considering that both giant pigmented nevus and meningioma originate from neural crest, they appear to be closely related each other. Such a combination of giant pigmented nevus and meningioma has not yet been reported. SN - 0009-918X UR - https://www.unboundmedicine.com/medline/citation/1395338/[A_case_of_giant_pigmented_nevus_with_multiple_meningiomas]_ DB - PRIME DP - Unbound Medicine ER -