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A comparative evaluation of metoprolol and methyldopa in the management of pregnancy induced hypertension.
Indian Heart J. 1992 Jan-Feb; 44(1):39-41.IH

Abstract

Thirty patients matched for age, parity, socioeconomic status and severity of pregnancy induced hypertension (PIH) were randomly allocated to treatment with metoprolol or methyldopa. The average fall in diastolic blood pressure was significant in the group treated with metoprolol as compared with the methyldopa group (p less than 0.01). There were 3 perinatal deaths in the methyldopa group and 1 in the metoprolol group; the mean birth weight of the babies was higher in cases treated with metoprolol. The results suggest metoprolol to be more efficacious with regard to control of hypertension and fetal outcome in cases of pregnancy induced hypertension.

Authors+Show Affiliations

Oumachigui A
Department of Obstetrics & Gynaecology, Jawaharlal Institute of Post-Graduate Medical Education and Research, Pondicherry.
Verghese M
No affiliation info available
Balachander J
No affiliation info available

MeSH

AdultBlood PressureFemaleHumansHypertensionInfant, NewbornMethyldopaMetoprololPregnancyPregnancy Complications, Cardiovascular

Pub Type(s)

Clinical Trial
Comparative Study
Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

1398694

Citation

Oumachigui, A, et al. "A Comparative Evaluation of Metoprolol and Methyldopa in the Management of Pregnancy Induced Hypertension." Indian Heart Journal, vol. 44, no. 1, 1992, pp. 39-41.
Oumachigui A, Verghese M, Balachander J. A comparative evaluation of metoprolol and methyldopa in the management of pregnancy induced hypertension. Indian Heart J. 1992;44(1):39-41.
Oumachigui, A., Verghese, M., & Balachander, J. (1992). A comparative evaluation of metoprolol and methyldopa in the management of pregnancy induced hypertension. Indian Heart Journal, 44(1), 39-41.
Oumachigui A, Verghese M, Balachander J. A Comparative Evaluation of Metoprolol and Methyldopa in the Management of Pregnancy Induced Hypertension. Indian Heart J. 1992 Jan-Feb;44(1):39-41. PubMed PMID: 1398694.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A comparative evaluation of metoprolol and methyldopa in the management of pregnancy induced hypertension. AU - Oumachigui,A, AU - Verghese,M, AU - Balachander,J, PY - 1992/1/1/pubmed PY - 1992/1/1/medline PY - 1992/1/1/entrez SP - 39 EP - 41 JF - Indian heart journal JO - Indian Heart J VL - 44 IS - 1 N2 - Thirty patients matched for age, parity, socioeconomic status and severity of pregnancy induced hypertension (PIH) were randomly allocated to treatment with metoprolol or methyldopa. The average fall in diastolic blood pressure was significant in the group treated with metoprolol as compared with the methyldopa group (p less than 0.01). There were 3 perinatal deaths in the methyldopa group and 1 in the metoprolol group; the mean birth weight of the babies was higher in cases treated with metoprolol. The results suggest metoprolol to be more efficacious with regard to control of hypertension and fetal outcome in cases of pregnancy induced hypertension. SN - 0019-4832 UR - https://www.unboundmedicine.com/medline/citation/1398694/A_comparative_evaluation_of_metoprolol_and_methyldopa_in_the_management_of_pregnancy_induced_hypertension_ DB - PRIME DP - Unbound Medicine ER -