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Radical microarteriolysis in the treatment of vasospastic disorders of the hand, especially scleroderma.
J Hand Surg Br. 1992 Aug; 17(4):447-52.JH

Abstract

Arterial spasm due to exaggerated sympathetic response is an important mechanism for Raynaud's phenomenon in scleroderma associated often with periadventitial scarring. The results of cervical sympathectomy have been unsatisfactory in the upper limb because of additional sympathetic pathways. Flatt therefore devised a distal sympathectomy by stripping the vessels of their adventitia over a short length of artery. The results of this operation were found by Wilgis in a large series to be poor in patients with scleroderma. A radical distal microarteriolysis including adventitia and surrounding scar is described and the results in 13 patients, 11 with scleroderma, are reported. Minimum follow-up is one year. All patients had relief from pain at rest and healing of painful ulceration. Mild recurrence of small ulcers was seen in only four patients.

Authors+Show Affiliations

Microsurgery Research Centre, St Vincent's Hospital, Fitzroy, Australia.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

1402276

Citation

O'Brien, B M., et al. "Radical Microarteriolysis in the Treatment of Vasospastic Disorders of the Hand, Especially Scleroderma." Journal of Hand Surgery (Edinburgh, Scotland), vol. 17, no. 4, 1992, pp. 447-52.
O'Brien BM, Kumar PA, Mellow CG, et al. Radical microarteriolysis in the treatment of vasospastic disorders of the hand, especially scleroderma. J Hand Surg Br. 1992;17(4):447-52.
O'Brien, B. M., Kumar, P. A., Mellow, C. G., & Oliver, T. V. (1992). Radical microarteriolysis in the treatment of vasospastic disorders of the hand, especially scleroderma. Journal of Hand Surgery (Edinburgh, Scotland), 17(4), 447-52.
O'Brien BM, et al. Radical Microarteriolysis in the Treatment of Vasospastic Disorders of the Hand, Especially Scleroderma. J Hand Surg Br. 1992;17(4):447-52. PubMed PMID: 1402276.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Radical microarteriolysis in the treatment of vasospastic disorders of the hand, especially scleroderma. AU - O'Brien,B M, AU - Kumar,P A, AU - Mellow,C G, AU - Oliver,T V, PY - 1992/8/1/pubmed PY - 1992/8/1/medline PY - 1992/8/1/entrez SP - 447 EP - 52 JF - Journal of hand surgery (Edinburgh, Scotland) JO - J Hand Surg Br VL - 17 IS - 4 N2 - Arterial spasm due to exaggerated sympathetic response is an important mechanism for Raynaud's phenomenon in scleroderma associated often with periadventitial scarring. The results of cervical sympathectomy have been unsatisfactory in the upper limb because of additional sympathetic pathways. Flatt therefore devised a distal sympathectomy by stripping the vessels of their adventitia over a short length of artery. The results of this operation were found by Wilgis in a large series to be poor in patients with scleroderma. A radical distal microarteriolysis including adventitia and surrounding scar is described and the results in 13 patients, 11 with scleroderma, are reported. Minimum follow-up is one year. All patients had relief from pain at rest and healing of painful ulceration. Mild recurrence of small ulcers was seen in only four patients. SN - 0266-7681 UR - https://www.unboundmedicine.com/medline/citation/1402276/Radical_microarteriolysis_in_the_treatment_of_vasospastic_disorders_of_the_hand_especially_scleroderma_ L2 - http://journals.sagepub.com/doi/full/10.1016/s0266-7681(05)80272-4?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -