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SecY and integral membrane components of the Escherichia coli protein translocation system.
Mol Microbiol 1992; 6(17):2423-8MM

Abstract

Genetic approaches can address the question of how integral membrane Sec factors interact with each other and facilitate protein translocation across the cytoplasmic membrane of E. coli. This review summarizes genetic analyses of SecY, SecE and some other protein translocation factors, utilizing 'prl' mutations, 'sec' mutations, 'suppressor-directed inactivation', 'Sec titration', dominant negative mutations and their suppressors. Evidence suggests that co-ordinate participation of SecY, SecE, SecD, SecF, and probably some other factors, is crucial for the process.

Authors+Show Affiliations

Institute for Virus Research, Kyoto University, Japan.

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

1406280

Citation

Ito, K. "SecY and Integral Membrane Components of the Escherichia Coli Protein Translocation System." Molecular Microbiology, vol. 6, no. 17, 1992, pp. 2423-8.
Ito K. SecY and integral membrane components of the Escherichia coli protein translocation system. Mol Microbiol. 1992;6(17):2423-8.
Ito, K. (1992). SecY and integral membrane components of the Escherichia coli protein translocation system. Molecular Microbiology, 6(17), pp. 2423-8.
Ito K. SecY and Integral Membrane Components of the Escherichia Coli Protein Translocation System. Mol Microbiol. 1992;6(17):2423-8. PubMed PMID: 1406280.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - SecY and integral membrane components of the Escherichia coli protein translocation system. A1 - Ito,K, PY - 1992/9/1/pubmed PY - 1992/9/1/medline PY - 1992/9/1/entrez SP - 2423 EP - 8 JF - Molecular microbiology JO - Mol. Microbiol. VL - 6 IS - 17 N2 - Genetic approaches can address the question of how integral membrane Sec factors interact with each other and facilitate protein translocation across the cytoplasmic membrane of E. coli. This review summarizes genetic analyses of SecY, SecE and some other protein translocation factors, utilizing 'prl' mutations, 'sec' mutations, 'suppressor-directed inactivation', 'Sec titration', dominant negative mutations and their suppressors. Evidence suggests that co-ordinate participation of SecY, SecE, SecD, SecF, and probably some other factors, is crucial for the process. SN - 0950-382X UR - https://www.unboundmedicine.com/medline/citation/1406280/SecY_and_integral_membrane_components_of_the_Escherichia_coli_protein_translocation_system_ L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0950-382X&date=1992&volume=6&issue=17&spage=2423 DB - PRIME DP - Unbound Medicine ER -