Tags

Type your tag names separated by a space and hit enter

Comparison of effects of lauric acid and palmitic acid on plasma lipids and lipoproteins.
Am J Clin Nutr 1992; 56(5):895-8AJ

Abstract

The effects of lauric acid (C12:0) on plasma lipids and lipoproteins were compared with the effects of palmitic acid (C16:0) and oleic acid (C18:1) in a metabolic-diet study of 14 men by using liquid-formula diets fed for 3 wk each in random order. Lauric acid was supplied in a synthetic high-lauric oil, palmitic acid was provided by palm oil and oleic acid in oleic-rich sunflower seed oil. The high-lauric oil resulted in higher concentrations of plasma total cholesterol (4.94 +/- 0.75 mmol/L [mean +/- SE]) and LDL cholesterol (3.70 +/- 0.57 mmol/L) when compared with high-oleic sunflower oil (4.44 +/- 0.54 and 3.31 +/- 0.44 mmol/L, respectively), but did not raise total and LDL cholesterol concentrations as much as did palm oil (5.17 +/- 0.65 and 3.93 +/- 0.51 mmol/L, respectively). No differences were noted in plasma triglycerides or HDL cholesterol. Lauric acid raises total and LDL cholesterol concentrations compared with oleic acid, but is not as potent for increasing cholesterol concentrations as is palmitic acid.

Authors+Show Affiliations

Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas.No affiliation info available

Pub Type(s)

Clinical Trial
Comparative Study
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

1415008

Citation

Denke, M A., and S M. Grundy. "Comparison of Effects of Lauric Acid and Palmitic Acid On Plasma Lipids and Lipoproteins." The American Journal of Clinical Nutrition, vol. 56, no. 5, 1992, pp. 895-8.
Denke MA, Grundy SM. Comparison of effects of lauric acid and palmitic acid on plasma lipids and lipoproteins. Am J Clin Nutr. 1992;56(5):895-8.
Denke, M. A., & Grundy, S. M. (1992). Comparison of effects of lauric acid and palmitic acid on plasma lipids and lipoproteins. The American Journal of Clinical Nutrition, 56(5), pp. 895-8.
Denke MA, Grundy SM. Comparison of Effects of Lauric Acid and Palmitic Acid On Plasma Lipids and Lipoproteins. Am J Clin Nutr. 1992;56(5):895-8. PubMed PMID: 1415008.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Comparison of effects of lauric acid and palmitic acid on plasma lipids and lipoproteins. AU - Denke,M A, AU - Grundy,S M, PY - 1992/11/1/pubmed PY - 1992/11/1/medline PY - 1992/11/1/entrez SP - 895 EP - 8 JF - The American journal of clinical nutrition JO - Am. J. Clin. Nutr. VL - 56 IS - 5 N2 - The effects of lauric acid (C12:0) on plasma lipids and lipoproteins were compared with the effects of palmitic acid (C16:0) and oleic acid (C18:1) in a metabolic-diet study of 14 men by using liquid-formula diets fed for 3 wk each in random order. Lauric acid was supplied in a synthetic high-lauric oil, palmitic acid was provided by palm oil and oleic acid in oleic-rich sunflower seed oil. The high-lauric oil resulted in higher concentrations of plasma total cholesterol (4.94 +/- 0.75 mmol/L [mean +/- SE]) and LDL cholesterol (3.70 +/- 0.57 mmol/L) when compared with high-oleic sunflower oil (4.44 +/- 0.54 and 3.31 +/- 0.44 mmol/L, respectively), but did not raise total and LDL cholesterol concentrations as much as did palm oil (5.17 +/- 0.65 and 3.93 +/- 0.51 mmol/L, respectively). No differences were noted in plasma triglycerides or HDL cholesterol. Lauric acid raises total and LDL cholesterol concentrations compared with oleic acid, but is not as potent for increasing cholesterol concentrations as is palmitic acid. SN - 0002-9165 UR - https://www.unboundmedicine.com/medline/citation/1415008/Comparison_of_effects_of_lauric_acid_and_palmitic_acid_on_plasma_lipids_and_lipoproteins_ L2 - https://academic.oup.com/ajcn/article-lookup/doi/10.1093/ajcn/56.5.895 DB - PRIME DP - Unbound Medicine ER -