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ON THE USE OF TRITIUM-LABELLED ALBUMIN FOR STUDIES OF INTESTINAL ABSORPTION.
Gut. 1964 Aug; 5:346-52.Gut

Abstract

Human serum albumin has been successfully labelled with tritium. It is considerably denatured in the process and has a shorter half life when given intravenously than (131)I-labelled albumin. Nevertheless it is satisfactory for absorption studies, although not for turnover observations. These studies on absorption in control subjects and in patients with intestinal malabsorption indicate that the excreted radioactivity may have been derived from endogenous sources rather than from the results of malabsorption alone.

Links

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Authors

JEEJEEBHOY KN
No affiliation info available
STEWART JH
No affiliation info available
EVANS EA
No affiliation info available
BOOTH CC
No affiliation info available

MeSH

Biomedical ResearchBlood Protein ElectrophoresisCeliac DiseaseChromatographyCrohn DiseaseDioxinsEnglandEnteritisFecesHumansIntestinal AbsorptionIntestine, SmallIntestinesMalabsorption SyndromesNitrogenPancreatitisPostgastrectomy SyndromesSerum AlbuminSodium ChlorideStatistics as TopicSurgical Procedures, OperativeTritium

Pub Type(s)

Journal Article

Language

eng

PubMed ID

14209918

Citation

JEEJEEBHOY, K N., et al. "ON the USE of TRITIUM-LABELLED ALBUMIN for STUDIES of INTESTINAL ABSORPTION." Gut, vol. 5, 1964, pp. 346-52.
JEEJEEBHOY KN, STEWART JH, EVANS EA, et al. ON THE USE OF TRITIUM-LABELLED ALBUMIN FOR STUDIES OF INTESTINAL ABSORPTION. Gut. 1964;5:346-52.
JEEJEEBHOY, K. N., STEWART, J. H., EVANS, E. A., & BOOTH, C. C. (1964). ON THE USE OF TRITIUM-LABELLED ALBUMIN FOR STUDIES OF INTESTINAL ABSORPTION. Gut, 5, 346-52.
JEEJEEBHOY KN, et al. ON the USE of TRITIUM-LABELLED ALBUMIN for STUDIES of INTESTINAL ABSORPTION. Gut. 1964;5:346-52. PubMed PMID: 14209918.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - ON THE USE OF TRITIUM-LABELLED ALBUMIN FOR STUDIES OF INTESTINAL ABSORPTION. AU - JEEJEEBHOY,K N, AU - STEWART,J H, AU - EVANS,E A, AU - BOOTH,C C, PY - 1964/8/1/pubmed PY - 1964/8/1/medline PY - 1964/8/1/entrez KW - BLOOD PROTEIN ELECTROPHORESIS KW - CHROMATOGRAPHY KW - CLINICAL RESEARCH KW - DIOXINS KW - ENGLAND KW - ENTERITIS, REGIONAL KW - FECES KW - INTESTINAL ABSORPTION KW - INTESTINE, SMALL KW - MALABSORPTION SYNDROMES KW - NITROGEN KW - PANCREATITIS KW - POSTGASTRECTOMY SYNDROMES KW - SERUM ALBUMIN KW - SODIUM CHLORIDE KW - SPRUE KW - STATISTICS KW - SURGERY, OPERATIVE KW - TRITIUM SP - 346 EP - 52 JF - Gut JO - Gut VL - 5 N2 - Human serum albumin has been successfully labelled with tritium. It is considerably denatured in the process and has a shorter half life when given intravenously than (131)I-labelled albumin. Nevertheless it is satisfactory for absorption studies, although not for turnover observations. These studies on absorption in control subjects and in patients with intestinal malabsorption indicate that the excreted radioactivity may have been derived from endogenous sources rather than from the results of malabsorption alone. SN - 0017-5749 UR - https://www.unboundmedicine.com/medline/citation/14209918/ON_THE_USE_OF_TRITIUM_LABELLED_ALBUMIN_FOR_STUDIES_OF_INTESTINAL_ABSORPTION_ DB - PRIME DP - Unbound Medicine ER -