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Efficacy of chlorhexidine and nystatin rinses in prevention of oral complications in leukemia and bone marrow transplantation.
Oral Surg Oral Med Oral Pathol. 1992 Jun; 73(6):682-9.OS

Abstract

The goal of reducing oral complications during chemotherapy and bone marrow transplantation has received attention at several centers. The current randomized study of 86 adults with leukemia treated with chemotherapy or bone marrow transplantation assessed the potential role of chlorhexidine, nystatin, and saline solution rinses to reduce the findings of oral mucositis, gingivitis, and oral infection. The results of this study did not show a reduction in mucositis with the use of these rinses. However, potential bacterial and fungal pathogens were identified less frequently in the patients using chlorhexidine rinse.

Authors+Show Affiliations

Vancouver General Hospital, British Columbia Cancer Agency, Canada.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

1437036

Citation

Epstein, J B., et al. "Efficacy of Chlorhexidine and Nystatin Rinses in Prevention of Oral Complications in Leukemia and Bone Marrow Transplantation." Oral Surgery, Oral Medicine, and Oral Pathology, vol. 73, no. 6, 1992, pp. 682-9.
Epstein JB, Vickars L, Spinelli J, et al. Efficacy of chlorhexidine and nystatin rinses in prevention of oral complications in leukemia and bone marrow transplantation. Oral Surg Oral Med Oral Pathol. 1992;73(6):682-9.
Epstein, J. B., Vickars, L., Spinelli, J., & Reece, D. (1992). Efficacy of chlorhexidine and nystatin rinses in prevention of oral complications in leukemia and bone marrow transplantation. Oral Surgery, Oral Medicine, and Oral Pathology, 73(6), 682-9.
Epstein JB, et al. Efficacy of Chlorhexidine and Nystatin Rinses in Prevention of Oral Complications in Leukemia and Bone Marrow Transplantation. Oral Surg Oral Med Oral Pathol. 1992;73(6):682-9. PubMed PMID: 1437036.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Efficacy of chlorhexidine and nystatin rinses in prevention of oral complications in leukemia and bone marrow transplantation. AU - Epstein,J B, AU - Vickars,L, AU - Spinelli,J, AU - Reece,D, PY - 1992/6/1/pubmed PY - 1992/6/1/medline PY - 1992/6/1/entrez SP - 682 EP - 9 JF - Oral surgery, oral medicine, and oral pathology JO - Oral Surg. Oral Med. Oral Pathol. VL - 73 IS - 6 N2 - The goal of reducing oral complications during chemotherapy and bone marrow transplantation has received attention at several centers. The current randomized study of 86 adults with leukemia treated with chemotherapy or bone marrow transplantation assessed the potential role of chlorhexidine, nystatin, and saline solution rinses to reduce the findings of oral mucositis, gingivitis, and oral infection. The results of this study did not show a reduction in mucositis with the use of these rinses. However, potential bacterial and fungal pathogens were identified less frequently in the patients using chlorhexidine rinse. SN - 0030-4220 UR - https://www.unboundmedicine.com/medline/citation/1437036/Efficacy_of_chlorhexidine_and_nystatin_rinses_in_prevention_of_oral_complications_in_leukemia_and_bone_marrow_transplantation_ L2 - http://www.diseaseinfosearch.org/result/7171 DB - PRIME DP - Unbound Medicine ER -