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Effects of alcohol consumption on mortality in patients with Type 2 diabetes mellitus.
Diabetologia 2003; 46(11):1581-5D

Abstract

AIMS/HYPOTHESIS

Moderate alcohol intake has been associated with increased life expectancy due to reduced mortality from cardiovascular disease. We prospectively examined the effects of alcohol consumption on mortality in Type 2 diabetic patients in Switzerland.

METHODS

A total of 287 patients with Type 2 diabetes mellitus (125 women, 162 men), recruited in Switzerland for the WHO Multinational Study of Vascular Disease in Diabetes, were included in this study. After a follow-up period of 12.6+/-0.6 years (means +/- SD), mortality from CHD and from all causes was assessed.

RESULTS

During the follow-up, 70 deaths occurred (21 from CHD, 49 from other causes). Compared with non-drinkers, alcohol consumers who drank alcohol 1 to 15 g, 16 to 30 g and 30 g or more per day had the following risk rates of death from CHD: 0.87 (95% CI: 0.25 to 2.51, NS), 0.00 (95% CI: 0.00 to 0.92, p less than 0.05) and 0.37 (95% CI, 0.01 to 2.42, NS), respectively. The corresponding risk rates of death from all causes were 1.27 (95% CI: 0.68 to 2.28, NS), 0.36 (95% CI: 0.09 to 0.99, p less than 0.05) and 1.66 (95% CI: 0.76 to 3.33, NS).

CONCLUSIONS/INTERPRETATION

In Swiss Type 2 diabetic patients moderate alcohol consumption of 16 to 30 g per day was associated with reduced mortality from CHD and from all causes. Alcohol intake above 30 g per day was associated with a tendency towards increased all-cause mortality.

Authors+Show Affiliations

Division of Endocrinology and Diabetes, University of Bern, Inselspital, Bern, Switzerland. peter.diem@insel.chNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Multicenter Study
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

14508652

Citation

Diem, P, et al. "Effects of Alcohol Consumption On Mortality in Patients With Type 2 Diabetes Mellitus." Diabetologia, vol. 46, no. 11, 2003, pp. 1581-5.
Diem P, Deplazes M, Fajfr R, et al. Effects of alcohol consumption on mortality in patients with Type 2 diabetes mellitus. Diabetologia. 2003;46(11):1581-5.
Diem, P., Deplazes, M., Fajfr, R., Bearth, A., Müller, B., Christ, E. R., & Teuscher, A. (2003). Effects of alcohol consumption on mortality in patients with Type 2 diabetes mellitus. Diabetologia, 46(11), pp. 1581-5.
Diem P, et al. Effects of Alcohol Consumption On Mortality in Patients With Type 2 Diabetes Mellitus. Diabetologia. 2003;46(11):1581-5. PubMed PMID: 14508652.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effects of alcohol consumption on mortality in patients with Type 2 diabetes mellitus. AU - Diem,P, AU - Deplazes,M, AU - Fajfr,R, AU - Bearth,A, AU - Müller,B, AU - Christ,E R, AU - Teuscher,A, Y1 - 2003/09/24/ PY - 2003/03/27/received PY - 2003/07/16/revised PY - 2003/9/26/pubmed PY - 2004/8/10/medline PY - 2003/9/26/entrez SP - 1581 EP - 5 JF - Diabetologia JO - Diabetologia VL - 46 IS - 11 N2 - AIMS/HYPOTHESIS: Moderate alcohol intake has been associated with increased life expectancy due to reduced mortality from cardiovascular disease. We prospectively examined the effects of alcohol consumption on mortality in Type 2 diabetic patients in Switzerland. METHODS: A total of 287 patients with Type 2 diabetes mellitus (125 women, 162 men), recruited in Switzerland for the WHO Multinational Study of Vascular Disease in Diabetes, were included in this study. After a follow-up period of 12.6+/-0.6 years (means +/- SD), mortality from CHD and from all causes was assessed. RESULTS: During the follow-up, 70 deaths occurred (21 from CHD, 49 from other causes). Compared with non-drinkers, alcohol consumers who drank alcohol 1 to 15 g, 16 to 30 g and 30 g or more per day had the following risk rates of death from CHD: 0.87 (95% CI: 0.25 to 2.51, NS), 0.00 (95% CI: 0.00 to 0.92, p less than 0.05) and 0.37 (95% CI, 0.01 to 2.42, NS), respectively. The corresponding risk rates of death from all causes were 1.27 (95% CI: 0.68 to 2.28, NS), 0.36 (95% CI: 0.09 to 0.99, p less than 0.05) and 1.66 (95% CI: 0.76 to 3.33, NS). CONCLUSIONS/INTERPRETATION: In Swiss Type 2 diabetic patients moderate alcohol consumption of 16 to 30 g per day was associated with reduced mortality from CHD and from all causes. Alcohol intake above 30 g per day was associated with a tendency towards increased all-cause mortality. SN - 0012-186X UR - https://www.unboundmedicine.com/medline/citation/14508652/Effects_of_alcohol_consumption_on_mortality_in_patients_with_Type_2_diabetes_mellitus_ L2 - https://dx.doi.org/10.1007/s00125-003-1209-2 DB - PRIME DP - Unbound Medicine ER -