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New eremophilane sesquiterpenes from Cacalia ainsliaeflora.
Planta Med. 2003 Aug; 69(8):745-9.PM

Abstract

One known eremophilanolide, 3beta-angeloyloxy-8beta,10beta-dihydroxy-6beta-methoxyeremophilenolide (1) and seven new eremophiane sesquiterpenes, 3beta-angeloyloxy-6beta-ethoxy-8beta,10beta-dihydroxyeremophilenolide (2), 3beta,6beta-diangeloyloxy-10alpha-hydroxy-8alpha-methoxyeremophilenolide, 6beta-angeloyloxy-8beta,10beta-dihydroxy-3-oxo-eremophilenolide, 6beta,8beta,10beta-trihydroxy-3-oxo-eremophilenolide, 3beta-angeloyloxy-6beta,10beta-dihydroxy-eremophila-7(11),8(9)-dien-8,12-olide (6), 3beta-angeloyloxy-10beta-hydroxy-6beta-methoxy-eremophila-7(11),8(9)-dien-8,12-olide, 3beta-angeloyloxy-8-oxo-eremophila-6.9-dien-12-oic acid ethyl ester, were isolated from the roots of Cacalia ainsliaeflora. Their structures were elucidated by spectroscopic methods. Compounds 1, 2 and 6 were assayed against both Gram-positive and Gram-negative bacteria. No positive activities were observed.

Authors+Show Affiliations

Mao M
Department of Chemistry, National Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou, PR China.
Yang Z
No affiliation info available
Jia Z
No affiliation info available

MeSH

Anti-Infective AgentsAsteraceaeGram-Negative BacteriaGram-Positive BacteriaHumansMagnetic Resonance SpectroscopyMicrobial Sensitivity TestsNaphthalenesPhytotherapyPlant ExtractsPlant RootsPolycyclic SesquiterpenesSesquiterpenes

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

14531026

Citation

Mao, Manjun, et al. "New Eremophilane Sesquiterpenes From Cacalia Ainsliaeflora." Planta Medica, vol. 69, no. 8, 2003, pp. 745-9.
Mao M, Yang Z, Jia Z. New eremophilane sesquiterpenes from Cacalia ainsliaeflora. Planta Med. 2003;69(8):745-9.
Mao, M., Yang, Z., & Jia, Z. (2003). New eremophilane sesquiterpenes from Cacalia ainsliaeflora. Planta Medica, 69(8), 745-9.
Mao M, Yang Z, Jia Z. New Eremophilane Sesquiterpenes From Cacalia Ainsliaeflora. Planta Med. 2003;69(8):745-9. PubMed PMID: 14531026.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - New eremophilane sesquiterpenes from Cacalia ainsliaeflora. AU - Mao,Manjun, AU - Yang,Zhongduo, AU - Jia,Zhongjian, PY - 2003/10/8/pubmed PY - 2003/12/3/medline PY - 2003/10/8/entrez SP - 745 EP - 9 JF - Planta medica JO - Planta Med VL - 69 IS - 8 N2 - One known eremophilanolide, 3beta-angeloyloxy-8beta,10beta-dihydroxy-6beta-methoxyeremophilenolide (1) and seven new eremophiane sesquiterpenes, 3beta-angeloyloxy-6beta-ethoxy-8beta,10beta-dihydroxyeremophilenolide (2), 3beta,6beta-diangeloyloxy-10alpha-hydroxy-8alpha-methoxyeremophilenolide, 6beta-angeloyloxy-8beta,10beta-dihydroxy-3-oxo-eremophilenolide, 6beta,8beta,10beta-trihydroxy-3-oxo-eremophilenolide, 3beta-angeloyloxy-6beta,10beta-dihydroxy-eremophila-7(11),8(9)-dien-8,12-olide (6), 3beta-angeloyloxy-10beta-hydroxy-6beta-methoxy-eremophila-7(11),8(9)-dien-8,12-olide, 3beta-angeloyloxy-8-oxo-eremophila-6.9-dien-12-oic acid ethyl ester, were isolated from the roots of Cacalia ainsliaeflora. Their structures were elucidated by spectroscopic methods. Compounds 1, 2 and 6 were assayed against both Gram-positive and Gram-negative bacteria. No positive activities were observed. SN - 0032-0943 UR - https://www.unboundmedicine.com/medline/citation/14531026/New_eremophilane_sesquiterpenes_from_Cacalia_ainsliaeflora_ DB - PRIME DP - Unbound Medicine ER -