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Schizophrenia and weight management: a systematic review of interventions to control weight.

Abstract

OBJECTIVE

Weight gain is a frequent side effect of antipsychotic medication which has serious implications for a patient's health and well being. This study systematically reviews the literature on the effectiveness of interventions designed to control weight gain in schizophrenia.

METHOD

A systematic search strategy was conducted of major databases in addition to citation searches. Study quality was rated.

RESULTS

Sixteen studies met the inclusion criteria. Five of eight pharmacological intervention studies reported small reductions in weight (<5% baseline body weight). All behavioural (including diet and/or exercise) interventions reported small reductions in, or maintenance of, weight.

CONCLUSION

Weight loss may be difficult but it is not impossible. Given the inconsistent results, the widespread use of pharmacological interventions cannot be recommended. Both dietary and exercise counselling set within a behavioural modification programme is necessary for sustained weight control.

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  • Publisher Full Text
  • Authors+Show Affiliations

    ,

    Faculty of Physical Education and Health, University of Toronto, Toronto, Ontario, Canada. guy.faulkner@utoronto.ca

    ,

    Source

    Acta psychiatrica Scandinavica 108:5 2003 Nov pg 324-32

    MeSH

    Antipsychotic Agents
    Appetite Depressants
    Behavior Therapy
    Clinical Trials as Topic
    Diet, Reducing
    Exercise
    Humans
    Obesity
    Schizophrenia
    Weight Gain

    Pub Type(s)

    Comparative Study
    Journal Article
    Review
    Systematic Review

    Language

    eng

    PubMed ID

    14531752

    Citation

    Faulkner, G, et al. "Schizophrenia and Weight Management: a Systematic Review of Interventions to Control Weight." Acta Psychiatrica Scandinavica, vol. 108, no. 5, 2003, pp. 324-32.
    Faulkner G, Soundy AA, Lloyd K. Schizophrenia and weight management: a systematic review of interventions to control weight. Acta Psychiatr Scand. 2003;108(5):324-32.
    Faulkner, G., Soundy, A. A., & Lloyd, K. (2003). Schizophrenia and weight management: a systematic review of interventions to control weight. Acta Psychiatrica Scandinavica, 108(5), pp. 324-32.
    Faulkner G, Soundy AA, Lloyd K. Schizophrenia and Weight Management: a Systematic Review of Interventions to Control Weight. Acta Psychiatr Scand. 2003;108(5):324-32. PubMed PMID: 14531752.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Schizophrenia and weight management: a systematic review of interventions to control weight. AU - Faulkner,G, AU - Soundy,A A, AU - Lloyd,K, PY - 2003/10/9/pubmed PY - 2004/4/2/medline PY - 2003/10/9/entrez SP - 324 EP - 32 JF - Acta psychiatrica Scandinavica JO - Acta Psychiatr Scand VL - 108 IS - 5 N2 - OBJECTIVE: Weight gain is a frequent side effect of antipsychotic medication which has serious implications for a patient's health and well being. This study systematically reviews the literature on the effectiveness of interventions designed to control weight gain in schizophrenia. METHOD: A systematic search strategy was conducted of major databases in addition to citation searches. Study quality was rated. RESULTS: Sixteen studies met the inclusion criteria. Five of eight pharmacological intervention studies reported small reductions in weight (<5% baseline body weight). All behavioural (including diet and/or exercise) interventions reported small reductions in, or maintenance of, weight. CONCLUSION: Weight loss may be difficult but it is not impossible. Given the inconsistent results, the widespread use of pharmacological interventions cannot be recommended. Both dietary and exercise counselling set within a behavioural modification programme is necessary for sustained weight control. SN - 0001-690X UR - https://www.unboundmedicine.com/medline/citation/14531752/full_citation L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&amp;sid=nlm:pubmed&amp;issn=0001-690X&amp;date=2003&amp;volume=108&amp;issue=5&amp;spage=324 DB - PRIME DP - Unbound Medicine ER -