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[Genotoxic and ecotoxic effects of urban waste water disinfected with sodium hypochlorite or peracetic acid].
Ann Ig. 2003 Jul-Aug; 15(4):277-302.AI

Abstract

Genotoxic and ecotoxicologic effects of urban wastewater disinfected with sodium hypochlorite or peracetic acid were analyzed. The formation of genotoxic species was studied by determining clastogenic and mutagenic activity of aqueous samples and their extracts with in vivo and in vitro tests, respectively. In particular, we have applied citogenetic tests to Allium cepa roots and Tradescantia inflorescence (Allium cepa test and Tradescantia/micronuclei test) and reversion test to Salmonella typhimurium according to the microsuspension procedure (Kado test). The latter is the method of choice for the analysis of complex matrices due to its high sensitivity and specificity. The mutagenic activity of disinfected effluents was similar to the corresponding untreated wastewater both sampled in four different periods. Therefore, the disinfection process did not seem to contribute to aquatic mutagenicity in the examined range of biocide concentration. The potential toxicity of disinfected wastewater for aquatic organisms was evaluated using Daphnia magna. The acute toxicity of peracetic acid in sewage was 0.4 mg/L (24 h E(L)C50). By comparing this value with peracetic acid concentrations detected in effluents from a pilot plant it is expected that treated wastewater would show acute toxic effects on aquatic organisms. Dissociation compounds (hydrogen peroxide and acetic acid) and possible by-products of peracetic acid did not seem to contribute significantly to the toxicity of sewage treated with peracetic acid.

Authors+Show Affiliations

Crebelli R
Lab. di Tossicologia Comparata ed Ecotossicologia, 1st. Superiore di Sanità, Roma.
Conti L
No affiliation info available
Marchini S
No affiliation info available
Monarca S
No affiliation info available
Feretti D
No affiliation info available
Zerbini I
No affiliation info available
Zani C
No affiliation info available
Veschetti E
No affiliation info available
Cutilli D
No affiliation info available
Ottaviani M
No affiliation info available

MeSH

Acetic AcidAlliumAnimalsDaphniaDisinfectantsGas Chromatography-Mass SpectrometryHydrogen PeroxideMicronucleus TestsMutagenicity TestsPeracetic AcidPilot ProjectsSalmonella typhimuriumSensitivity and SpecificitySodium HypochloriteTradescantiaUrban HealthWaste Disposal, FluidWater Pollutants, Chemical

Pub Type(s)

English Abstract
Journal Article
Research Support, Non-U.S. Gov't

Language

ita

PubMed ID

14552196

Citation

Crebelli, R, et al. "[Genotoxic and Ecotoxic Effects of Urban Waste Water Disinfected With Sodium Hypochlorite or Peracetic Acid]." Annali Di Igiene : Medicina Preventiva E Di Comunita, vol. 15, no. 4, 2003, pp. 277-302.
Crebelli R, Conti L, Marchini S, et al. [Genotoxic and ecotoxic effects of urban waste water disinfected with sodium hypochlorite or peracetic acid]. Ann Ig. 2003;15(4):277-302.
Crebelli, R., Conti, L., Marchini, S., Monarca, S., Feretti, D., Zerbini, I., Zani, C., Veschetti, E., Cutilli, D., & Ottaviani, M. (2003). [Genotoxic and ecotoxic effects of urban waste water disinfected with sodium hypochlorite or peracetic acid]. Annali Di Igiene : Medicina Preventiva E Di Comunita, 15(4), 277-302.
Crebelli R, et al. [Genotoxic and Ecotoxic Effects of Urban Waste Water Disinfected With Sodium Hypochlorite or Peracetic Acid]. Ann Ig. 2003 Jul-Aug;15(4):277-302. PubMed PMID: 14552196.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Genotoxic and ecotoxic effects of urban waste water disinfected with sodium hypochlorite or peracetic acid]. AU - Crebelli,R, AU - Conti,L, AU - Marchini,S, AU - Monarca,S, AU - Feretti,D, AU - Zerbini,I, AU - Zani,C, AU - Veschetti,E, AU - Cutilli,D, AU - Ottaviani,M, PY - 2003/10/14/pubmed PY - 2003/12/13/medline PY - 2003/10/14/entrez SP - 277 EP - 302 JF - Annali di igiene : medicina preventiva e di comunita JO - Ann Ig VL - 15 IS - 4 N2 - Genotoxic and ecotoxicologic effects of urban wastewater disinfected with sodium hypochlorite or peracetic acid were analyzed. The formation of genotoxic species was studied by determining clastogenic and mutagenic activity of aqueous samples and their extracts with in vivo and in vitro tests, respectively. In particular, we have applied citogenetic tests to Allium cepa roots and Tradescantia inflorescence (Allium cepa test and Tradescantia/micronuclei test) and reversion test to Salmonella typhimurium according to the microsuspension procedure (Kado test). The latter is the method of choice for the analysis of complex matrices due to its high sensitivity and specificity. The mutagenic activity of disinfected effluents was similar to the corresponding untreated wastewater both sampled in four different periods. Therefore, the disinfection process did not seem to contribute to aquatic mutagenicity in the examined range of biocide concentration. The potential toxicity of disinfected wastewater for aquatic organisms was evaluated using Daphnia magna. The acute toxicity of peracetic acid in sewage was 0.4 mg/L (24 h E(L)C50). By comparing this value with peracetic acid concentrations detected in effluents from a pilot plant it is expected that treated wastewater would show acute toxic effects on aquatic organisms. Dissociation compounds (hydrogen peroxide and acetic acid) and possible by-products of peracetic acid did not seem to contribute significantly to the toxicity of sewage treated with peracetic acid. SN - 1120-9135 UR - https://www.unboundmedicine.com/medline/citation/14552196/[Genotoxic_and_ecotoxic_effects_of_urban_waste_water_disinfected_with_sodium_hypochlorite_or_peracetic_acid]_ DB - PRIME DP - Unbound Medicine ER -