Tags

Type your tag names separated by a space and hit enter

Evaluation of an oral preventive protocol in children with acute lymphoblastic leukemia.
Pesqui Odontol Bras 2003 Apr-Jun; 17(2):147-50PO

Abstract

This study was designed to assess the effectiveness of a preventive oral protocol in children receiving antineoplastic treatment for acute lymphoblastic leukemia (ALL) before initiating a larger intervention study. During a seven month period, fourteen children from two to ten years old with a diagnosis of ALL were evaluated. Patients with ALL who received a 0.12% chlorhexidine mouth rinse (seven children) were compared to a control group of patients who were not given the same preventive treatment (seven children) as to the occurrence of oral mucosal complications. Children in both groups received daily oral hygiene care, and were examined daily by the pediatric dentistry team until discharge. A significant decrease in the incidence of oral mucositis and ulceration was observed in the children who received a 0.12% chlorhexidine mouth rinse (p < 0.05 by Fisher's exact test). The findings obtained in the present trial are encouraging, and suggest that the systematic application of a preventive protocol reduces the incidence of oral complications in children with ALL receiving chemotherapy.

Authors+Show Affiliations

School of Dentistry, Potiguar University, Brazil.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Evaluation Studies
Journal Article

Language

eng

PubMed ID

14569357

Citation

Costa, Edja Maria Melo de Brito, et al. "Evaluation of an Oral Preventive Protocol in Children With Acute Lymphoblastic Leukemia." Pesquisa Odontologica Brasileira = Brazilian Oral Research, vol. 17, no. 2, 2003, pp. 147-50.
Costa EM, Fernandes MZ, Quinder LB, et al. Evaluation of an oral preventive protocol in children with acute lymphoblastic leukemia. Pesqui Odontol Bras. 2003;17(2):147-50.
Costa, E. M., Fernandes, M. Z., Quinder, L. B., de Souza, L. B., & Pinto, L. P. (2003). Evaluation of an oral preventive protocol in children with acute lymphoblastic leukemia. Pesquisa Odontologica Brasileira = Brazilian Oral Research, 17(2), pp. 147-50.
Costa EM, et al. Evaluation of an Oral Preventive Protocol in Children With Acute Lymphoblastic Leukemia. Pesqui Odontol Bras. 2003;17(2):147-50. PubMed PMID: 14569357.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Evaluation of an oral preventive protocol in children with acute lymphoblastic leukemia. AU - Costa,Edja Maria Melo de Brito, AU - Fernandes,Maria Zélia, AU - Quinder,Lêda Bezerra, AU - de Souza,Lélia Batista, AU - Pinto,Leão Pereira, Y1 - 2003/10/10/ PY - 2003/10/22/pubmed PY - 2004/1/31/medline PY - 2003/10/22/entrez SP - 147 EP - 50 JF - Pesquisa odontologica brasileira = Brazilian oral research JO - Pesqui Odontol Bras VL - 17 IS - 2 N2 - This study was designed to assess the effectiveness of a preventive oral protocol in children receiving antineoplastic treatment for acute lymphoblastic leukemia (ALL) before initiating a larger intervention study. During a seven month period, fourteen children from two to ten years old with a diagnosis of ALL were evaluated. Patients with ALL who received a 0.12% chlorhexidine mouth rinse (seven children) were compared to a control group of patients who were not given the same preventive treatment (seven children) as to the occurrence of oral mucosal complications. Children in both groups received daily oral hygiene care, and were examined daily by the pediatric dentistry team until discharge. A significant decrease in the incidence of oral mucositis and ulceration was observed in the children who received a 0.12% chlorhexidine mouth rinse (p < 0.05 by Fisher's exact test). The findings obtained in the present trial are encouraging, and suggest that the systematic application of a preventive protocol reduces the incidence of oral complications in children with ALL receiving chemotherapy. SN - 1517-7491 UR - https://www.unboundmedicine.com/medline/citation/14569357/Evaluation_of_an_oral_preventive_protocol_in_children_with_acute_lymphoblastic_leukemia_ L2 - http://www.diseaseinfosearch.org/result/188 DB - PRIME DP - Unbound Medicine ER -