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Splenic embolization in treatment of portal vein occlusion deferring liver transplantation.
Hepatogastroenterology. 2003 Sep-Oct; 50(53):1614-6.H

Abstract

The number of liver transplantations performed in this country is limited to the availability of cadaver liver donors, which are always short of demand. Deterioration of patient's clinical condition during the long wait for a compatible donor usually casts a poor prognosis on the patient. We report a 6-year-old girl who underwent splenic artery embolization as an alternative procedure due to a life-threatening clinical condition while liver graft was not immediately available. She was a case of idiopathic portal hypertension with portal vein occlusion that had resulted in splenomegaly, pancytopenia, gastric and esophageal varices. Living graft transplantation was contraindicated due to portal vein lesion. She was listed as high-urgency for liver transplantation as she developed repeated esophageal variceal bleeding requiring frequent sclerotherapy and admission to the intensive care unit. Prevention of the ongoing worsening clinical complications, improvement of hematological disorders and correction of hypersplenism was achieved right after splenic artery embolization. The patient resumed normal daily life and has been successfully eliminated from the waiting list of liver transplantation. We conclude that this is a safe and effective alternative to splenectomy that might call of further liver transplantation.

Authors+Show Affiliations

Department of Diagnostic Radiology, Liver Transplant Program, Chang Gung University, Chang Gung Memorial Hospital, Kaohsiung Medical Center, Kaohsiung 83305, Taiwan. cheng.yufan@msa.hinet.netNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

14571797

Citation

Cheng, Yu Fan, et al. "Splenic Embolization in Treatment of Portal Vein Occlusion Deferring Liver Transplantation." Hepato-gastroenterology, vol. 50, no. 53, 2003, pp. 1614-6.
Cheng YF, Chen CL, Chen TY, et al. Splenic embolization in treatment of portal vein occlusion deferring liver transplantation. Hepatogastroenterology. 2003;50(53):1614-6.
Cheng, Y. F., Chen, C. L., Chen, T. Y., Huang, T. L., Chen, Y. S., Tsang, L. L., & Sun, P. L. (2003). Splenic embolization in treatment of portal vein occlusion deferring liver transplantation. Hepato-gastroenterology, 50(53), 1614-6.
Cheng YF, et al. Splenic Embolization in Treatment of Portal Vein Occlusion Deferring Liver Transplantation. Hepatogastroenterology. 2003 Sep-Oct;50(53):1614-6. PubMed PMID: 14571797.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Splenic embolization in treatment of portal vein occlusion deferring liver transplantation. AU - Cheng,Yu Fan, AU - Chen,Chao Long, AU - Chen,Tai Yi, AU - Huang,Tung Liang, AU - Chen,Yaw Sen, AU - Tsang,Leo Leung-chit, AU - Sun,Po Lin, PY - 2003/10/24/pubmed PY - 2004/2/26/medline PY - 2003/10/24/entrez SP - 1614 EP - 6 JF - Hepato-gastroenterology JO - Hepatogastroenterology VL - 50 IS - 53 N2 - The number of liver transplantations performed in this country is limited to the availability of cadaver liver donors, which are always short of demand. Deterioration of patient's clinical condition during the long wait for a compatible donor usually casts a poor prognosis on the patient. We report a 6-year-old girl who underwent splenic artery embolization as an alternative procedure due to a life-threatening clinical condition while liver graft was not immediately available. She was a case of idiopathic portal hypertension with portal vein occlusion that had resulted in splenomegaly, pancytopenia, gastric and esophageal varices. Living graft transplantation was contraindicated due to portal vein lesion. She was listed as high-urgency for liver transplantation as she developed repeated esophageal variceal bleeding requiring frequent sclerotherapy and admission to the intensive care unit. Prevention of the ongoing worsening clinical complications, improvement of hematological disorders and correction of hypersplenism was achieved right after splenic artery embolization. The patient resumed normal daily life and has been successfully eliminated from the waiting list of liver transplantation. We conclude that this is a safe and effective alternative to splenectomy that might call of further liver transplantation. SN - 0172-6390 UR - https://www.unboundmedicine.com/medline/citation/14571797/Splenic_embolization_in_treatment_of_portal_vein_occlusion_deferring_liver_transplantation_ L2 - http://www.diseaseinfosearch.org/result/7171 DB - PRIME DP - Unbound Medicine ER -