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Alcohol use and risk of non-Hodgkin's lymphoma among Connecticut women (United States).
Cancer Causes Control 2003; 14(7):687-94CC

Abstract

OBJECTIVE

Incidence rates of non-Hodgkin's lymphoma (NHL) have risen dramatically over the past several decades; however, the etiology of NHL remains largely unknown. Previous studies of the relationship between alcohol consumption and NHL have yielded conflicting results. Data from a population-based case-control study among women in Connecticut were analyzed to determine the potential impact of alcohol consumption on risk of NHL.

METHODS

The study included 601 histologically confirmed, incident cases of NHL and 718 population-based controls. In-person interviews were administered using standardized, structured questionnaires to collect data on history of consumption for beer, wine, and liquor.

RESULTS

When compared to non-drinkers, women who reported consumption of at least 12 drinks per year of any type of alcohol experienced slightly reduced risk of NHL (OR: 0.82; 95% CI: 0.65-1.04). Further stratification by alcohol type revealed that the inverse association was mainly limited to wine consumption (OR: 0.75; 95% CI: 0.59-0.96), with no clear association for beer or liquor consumption. Risk of NHL was further reduced with increasing duration of wine consumption (p for linear trend = 0.02). Consumption of wine for greater than 40 years was associated with approximately 40% reduction in risk (OR: 0.63; 95% CI: 0.44-0.91).

CONCLUSION

Our results are consistent with several recent epidemiologic studies that have also suggested an inverse association between wine consumption and risk of NHL. The reduction in risk of NHL associated with increased duration of wine consumption warrants further investigation in other populations.

Authors+Show Affiliations

Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut 06520, USA.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

14575367

Citation

Morton, Lindsay McOmber, et al. "Alcohol Use and Risk of non-Hodgkin's Lymphoma Among Connecticut Women (United States)." Cancer Causes & Control : CCC, vol. 14, no. 7, 2003, pp. 687-94.
Morton LM, Holford TR, Leaderer B, et al. Alcohol use and risk of non-Hodgkin's lymphoma among Connecticut women (United States). Cancer Causes Control. 2003;14(7):687-94.
Morton, L. M., Holford, T. R., Leaderer, B., Zhang, Y., Zahm, S. H., Boyle, P., ... Zheng, T. (2003). Alcohol use and risk of non-Hodgkin's lymphoma among Connecticut women (United States). Cancer Causes & Control : CCC, 14(7), pp. 687-94.
Morton LM, et al. Alcohol Use and Risk of non-Hodgkin's Lymphoma Among Connecticut Women (United States). Cancer Causes Control. 2003;14(7):687-94. PubMed PMID: 14575367.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Alcohol use and risk of non-Hodgkin's lymphoma among Connecticut women (United States). AU - Morton,Lindsay McOmber, AU - Holford,Theodore R, AU - Leaderer,Brian, AU - Zhang,Yawei, AU - Zahm,Shelia Hoar, AU - Boyle,Peter, AU - Flynn,Stuart, AU - Tallini,Giovanni, AU - Owens,Patricia H, AU - Zhang,Bing, AU - Zheng,Tongzhang, PY - 2003/10/25/pubmed PY - 2004/2/28/medline PY - 2003/10/25/entrez SP - 687 EP - 94 JF - Cancer causes & control : CCC JO - Cancer Causes Control VL - 14 IS - 7 N2 - OBJECTIVE: Incidence rates of non-Hodgkin's lymphoma (NHL) have risen dramatically over the past several decades; however, the etiology of NHL remains largely unknown. Previous studies of the relationship between alcohol consumption and NHL have yielded conflicting results. Data from a population-based case-control study among women in Connecticut were analyzed to determine the potential impact of alcohol consumption on risk of NHL. METHODS: The study included 601 histologically confirmed, incident cases of NHL and 718 population-based controls. In-person interviews were administered using standardized, structured questionnaires to collect data on history of consumption for beer, wine, and liquor. RESULTS: When compared to non-drinkers, women who reported consumption of at least 12 drinks per year of any type of alcohol experienced slightly reduced risk of NHL (OR: 0.82; 95% CI: 0.65-1.04). Further stratification by alcohol type revealed that the inverse association was mainly limited to wine consumption (OR: 0.75; 95% CI: 0.59-0.96), with no clear association for beer or liquor consumption. Risk of NHL was further reduced with increasing duration of wine consumption (p for linear trend = 0.02). Consumption of wine for greater than 40 years was associated with approximately 40% reduction in risk (OR: 0.63; 95% CI: 0.44-0.91). CONCLUSION: Our results are consistent with several recent epidemiologic studies that have also suggested an inverse association between wine consumption and risk of NHL. The reduction in risk of NHL associated with increased duration of wine consumption warrants further investigation in other populations. SN - 0957-5243 UR - https://www.unboundmedicine.com/medline/citation/14575367/Alcohol_use_and_risk_of_non_Hodgkin's_lymphoma_among_Connecticut_women__United_States__ L2 - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=linkout&SEARCH=14575367.ui DB - PRIME DP - Unbound Medicine ER -