Tags

Type your tag names separated by a space and hit enter

A cross-sectional retrospective assessment of anti-arthritic drugs in patients with arthritis in Korea.
Curr Med Res Opin. 2003; 19(7):597-602.CM

Abstract

BACKGROUND

Selective cyclo-oxygenase-2 (COX-2) inhibitors were recently introduced for the treatment of arthritis because of their lower rates of gastrointestinal adverse events compared with traditional non-steroidal anti-inflammatory drugs (NSAIDs).

OBJECTIVE

To examine the medication usage patterns for both osteoarthritis (OA) and rheumatoid arthritis (RA) in Korea.

METHODS

The medical charts of a convenience sample of 402 patients with OA or RA were reviewed by the Arthritis Study Group in 14 hospitals and ten clinics in Korea.

RESULTS

Traditional oral NSAIDs were the most commonly prescribed drugs for OA (68.3%) and RA (65.1%) patients. Two-thirds (66.7%) of the RA patients taking COX-2 inhibitors were prescribed other arthritis medications concurrently and 85.1% of RA patients taking NSAIDs were prescribed other arthritis medications concurrently. Patients on NSAIDs were almost twice as likely to have a gastroprotective agent (GPA) concurrently compared to COX-2 inhibitor users (OA patients 38.1% vs 21.2%; RA patients 57.9% vs 30.6%). Overall, patients taking COX-2 inhibitors were less likely to take GPAs concurrently compared to patients not taking COX-2 inhibitors (unadjusted OR 0.36; adjusted OR 0.39).

CONCLUSIONS

Traditional oral NSAIDs were commonly prescribed to arthritis patients in Korea. In this study, patients taking COX-2 inhibitors were prescribed less adjunctive arthritis treatments and less gastroprotective agents than traditional oral NSAID users.

Authors+Show Affiliations

Seoul National University Hospital, Seoul, Korea.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Multicenter Study
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

14606981

Citation

Lee, Myung Chul, et al. "A Cross-sectional Retrospective Assessment of Anti-arthritic Drugs in Patients With Arthritis in Korea." Current Medical Research and Opinion, vol. 19, no. 7, 2003, pp. 597-602.
Lee MC, Lee S, Suh DC, et al. A cross-sectional retrospective assessment of anti-arthritic drugs in patients with arthritis in Korea. Curr Med Res Opin. 2003;19(7):597-602.
Lee, M. C., Lee, S., Suh, D. C., Kim, J., & Kong, S. X. (2003). A cross-sectional retrospective assessment of anti-arthritic drugs in patients with arthritis in Korea. Current Medical Research and Opinion, 19(7), 597-602.
Lee MC, et al. A Cross-sectional Retrospective Assessment of Anti-arthritic Drugs in Patients With Arthritis in Korea. Curr Med Res Opin. 2003;19(7):597-602. PubMed PMID: 14606981.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A cross-sectional retrospective assessment of anti-arthritic drugs in patients with arthritis in Korea. AU - Lee,Myung Chul, AU - Lee,Seokhyun, AU - Suh,Dong-Churl, AU - Kim,Jeeyeon, AU - Kong,Sheldon X, AU - ,, PY - 2003/11/11/pubmed PY - 2004/2/24/medline PY - 2003/11/11/entrez SP - 597 EP - 602 JF - Current medical research and opinion JO - Curr Med Res Opin VL - 19 IS - 7 N2 - BACKGROUND: Selective cyclo-oxygenase-2 (COX-2) inhibitors were recently introduced for the treatment of arthritis because of their lower rates of gastrointestinal adverse events compared with traditional non-steroidal anti-inflammatory drugs (NSAIDs). OBJECTIVE: To examine the medication usage patterns for both osteoarthritis (OA) and rheumatoid arthritis (RA) in Korea. METHODS: The medical charts of a convenience sample of 402 patients with OA or RA were reviewed by the Arthritis Study Group in 14 hospitals and ten clinics in Korea. RESULTS: Traditional oral NSAIDs were the most commonly prescribed drugs for OA (68.3%) and RA (65.1%) patients. Two-thirds (66.7%) of the RA patients taking COX-2 inhibitors were prescribed other arthritis medications concurrently and 85.1% of RA patients taking NSAIDs were prescribed other arthritis medications concurrently. Patients on NSAIDs were almost twice as likely to have a gastroprotective agent (GPA) concurrently compared to COX-2 inhibitor users (OA patients 38.1% vs 21.2%; RA patients 57.9% vs 30.6%). Overall, patients taking COX-2 inhibitors were less likely to take GPAs concurrently compared to patients not taking COX-2 inhibitors (unadjusted OR 0.36; adjusted OR 0.39). CONCLUSIONS: Traditional oral NSAIDs were commonly prescribed to arthritis patients in Korea. In this study, patients taking COX-2 inhibitors were prescribed less adjunctive arthritis treatments and less gastroprotective agents than traditional oral NSAID users. SN - 0300-7995 UR - https://www.unboundmedicine.com/medline/citation/14606981/A_cross_sectional_retrospective_assessment_of_anti_arthritic_drugs_in_patients_with_arthritis_in_Korea_ L2 - https://www.tandfonline.com/doi/full/10.1185/030079903125002252 DB - PRIME DP - Unbound Medicine ER -