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Leg ulceration in venous disease.
Postgrad Med J. 1992 Oct; 68(804):779-85.PM

Abstract

We have given a brief summary of the scale of the problem caused by venous ulceration in the UK, and have then reviewed the various theories of causation, including a historical survey, and presented the evidence for and against the two main current theories of fibrin cuffs and white cell trapping. We also outline previous hypotheses of the aetiology of venous ulceration, including arteriovenous microanastomoses, stasis and oedema. The contribution of superficial venous incompetence in the pathogenesis of ulceration is also examined.

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Authors+Show Affiliations

Shami SK
Department of Surgery, University College and Middlesex School of Medicine, Middlesex Hospital, London, UK.
Shields DA
No affiliation info available
Scurr JH
No affiliation info available
Smith PD
No affiliation info available

MeSH

Arteriovenous FistulaCapillary PermeabilityEdemaFibrinHumansRegional Blood FlowVaricose UlcerVenous Insufficiency

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

1461849

Citation

Shami, S K., et al. "Leg Ulceration in Venous Disease." Postgraduate Medical Journal, vol. 68, no. 804, 1992, pp. 779-85.
Shami SK, Shields DA, Scurr JH, et al. Leg ulceration in venous disease. Postgrad Med J. 1992;68(804):779-85.
Shami, S. K., Shields, D. A., Scurr, J. H., & Smith, P. D. (1992). Leg ulceration in venous disease. Postgraduate Medical Journal, 68(804), 779-85.
Shami SK, et al. Leg Ulceration in Venous Disease. Postgrad Med J. 1992;68(804):779-85. PubMed PMID: 1461849.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Leg ulceration in venous disease. AU - Shami,S K, AU - Shields,D A, AU - Scurr,J H, AU - Smith,P D, PY - 1992/10/1/pubmed PY - 1992/10/1/medline PY - 1992/10/1/entrez SP - 779 EP - 85 JF - Postgraduate medical journal JO - Postgrad Med J VL - 68 IS - 804 N2 - We have given a brief summary of the scale of the problem caused by venous ulceration in the UK, and have then reviewed the various theories of causation, including a historical survey, and presented the evidence for and against the two main current theories of fibrin cuffs and white cell trapping. We also outline previous hypotheses of the aetiology of venous ulceration, including arteriovenous microanastomoses, stasis and oedema. The contribution of superficial venous incompetence in the pathogenesis of ulceration is also examined. SN - 0032-5473 UR - https://www.unboundmedicine.com/medline/citation/1461849/Leg_ulceration_in_venous_disease_ DB - PRIME DP - Unbound Medicine ER -