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[Microbiological evaluation of the effectiveness of gynalgin in the treatment of vaginitis].
Wiad Lek. 1992 Apr; 45(7-8):263-9.WL

Abstract

The microbiological effectiveness of the preparation Gynalgin produced by POLFA Pharmaceutical Works in Rzeszów was assessed in cases of vulvovaginitis in 55 patients with clinically diagnosed inflammatory conditions of the lower genital tract, who were given Gynalgin tablets in 10-day courses. Vaginal smears were examined three times for the presence of bacteria, fungi and trichomonas vaginalis (before and immediately after the treatment, and two weeks later). In the initial examination in five vaginal smears mixed bacterial flora was found, in 6 smears trichomonas was present, in 4--bacteria and fungi, and in one--trichomonas and fungi. After the treatment in control examinations I and II the number of the isolated bacterial strains was lower, trichomonas was no longer present, and the number of fungi was reduced evidently. In the light of these microbiological examinations Gynalgin was found to exert a strong fungicidal, bactericidal and antitrichomonal activity, and the results of laboratory investigations agreed with those of clinical trials of Gynalgin effectiveness.

Authors+Show Affiliations

Sikorski R
Kliniki Ginekologii Instytutu Połoznictwa i Chorób Kobiecych Ak. Med., Lublinie.
Hencner Z
No affiliation info available
Gliński Z
No affiliation info available
Wawrzkiewicz K
No affiliation info available
Radomański T
No affiliation info available
Milart P
No affiliation info available
Paszkowski T
No affiliation info available
Skrzypczak W
No affiliation info available
Sławiński P
No affiliation info available
Maruszak E
No affiliation info available

MeSH

AnimalsAnti-Infective Agents, LocalAntifungal AgentsAntitrichomonal AgentsBacterial InfectionsCandida albicansCandidiasis, VulvovaginalChlorquinaldolDrug CombinationsEscherichia coliFemaleGram-Positive BacteriaHumansIn Vitro TechniquesMetronidazoleTrichomonas VaginitisTrichomonas vaginalisVulvovaginitis

Pub Type(s)

Clinical Trial
Comparative Study
Journal Article

Language

pol

PubMed ID

1462586

Citation

Sikorski, R, et al. "[Microbiological Evaluation of the Effectiveness of Gynalgin in the Treatment of Vaginitis]." Wiadomosci Lekarskie (Warsaw, Poland : 1960), vol. 45, no. 7-8, 1992, pp. 263-9.
Sikorski R, Hencner Z, Gliński Z, et al. [Microbiological evaluation of the effectiveness of gynalgin in the treatment of vaginitis]. Wiad Lek. 1992;45(7-8):263-9.
Sikorski, R., Hencner, Z., Gliński, Z., Wawrzkiewicz, K., Radomański, T., Milart, P., Paszkowski, T., Skrzypczak, W., Sławiński, P., & Maruszak, E. (1992). [Microbiological evaluation of the effectiveness of gynalgin in the treatment of vaginitis]. Wiadomosci Lekarskie (Warsaw, Poland : 1960), 45(7-8), 263-9.
Sikorski R, et al. [Microbiological Evaluation of the Effectiveness of Gynalgin in the Treatment of Vaginitis]. Wiad Lek. 1992;45(7-8):263-9. PubMed PMID: 1462586.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Microbiological evaluation of the effectiveness of gynalgin in the treatment of vaginitis]. AU - Sikorski,R, AU - Hencner,Z, AU - Gliński,Z, AU - Wawrzkiewicz,K, AU - Radomański,T, AU - Milart,P, AU - Paszkowski,T, AU - Skrzypczak,W, AU - Sławiński,P, AU - Maruszak,E, PY - 1992/4/1/pubmed PY - 1992/4/1/medline PY - 1992/4/1/entrez SP - 263 EP - 9 JF - Wiadomosci lekarskie (Warsaw, Poland : 1960) JO - Wiad Lek VL - 45 IS - 7-8 N2 - The microbiological effectiveness of the preparation Gynalgin produced by POLFA Pharmaceutical Works in Rzeszów was assessed in cases of vulvovaginitis in 55 patients with clinically diagnosed inflammatory conditions of the lower genital tract, who were given Gynalgin tablets in 10-day courses. Vaginal smears were examined three times for the presence of bacteria, fungi and trichomonas vaginalis (before and immediately after the treatment, and two weeks later). In the initial examination in five vaginal smears mixed bacterial flora was found, in 6 smears trichomonas was present, in 4--bacteria and fungi, and in one--trichomonas and fungi. After the treatment in control examinations I and II the number of the isolated bacterial strains was lower, trichomonas was no longer present, and the number of fungi was reduced evidently. In the light of these microbiological examinations Gynalgin was found to exert a strong fungicidal, bactericidal and antitrichomonal activity, and the results of laboratory investigations agreed with those of clinical trials of Gynalgin effectiveness. SN - 0043-5147 UR - https://www.unboundmedicine.com/medline/citation/1462586/[Microbiological_evaluation_of_the_effectiveness_of_gynalgin_in_the_treatment_of_vaginitis]_ DB - PRIME DP - Unbound Medicine ER -