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Antimicrobial and cytotoxicity evaluation of Buchholzia coriacea stem bark.
Fitoterapia. 2003 Dec; 74(7-8):706-9.F

Abstract

Fractions prepared from the methanol extract of Buchholzia coriacea stem bark exhibited a high concentration-dependent antibacterial and antifungal activity compared to the standard antibiotics, ampicillin and tioconazole. In the brine shrimp lethality (BSL) assay, the methanol extract was found to be non-toxic with an LC(50) of 1031 microg/ml. The two main compounds present in the most active fraction were isolated and identified as lupeol and beta-sitosterol.

Authors+Show Affiliations

Ajaiyeoba EO
Department of Pharmacognosy, University of Ibadan, Ibadan, Nigeria. edajaiye@yahoo.com
Onocha PA
No affiliation info available
Nwozo SO
No affiliation info available
Sama W
No affiliation info available

MeSH

AnimalsAnti-Infective AgentsArtemiaAspergillus flavusBacteriaCandida albicansHumansLethal Dose 50Microbial Sensitivity TestsPhytotherapyPlant BarkPlant ExtractsTriterpenes

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

14630180

Citation

Ajaiyeoba, E O., et al. "Antimicrobial and Cytotoxicity Evaluation of Buchholzia Coriacea Stem Bark." Fitoterapia, vol. 74, no. 7-8, 2003, pp. 706-9.
Ajaiyeoba EO, Onocha PA, Nwozo SO, et al. Antimicrobial and cytotoxicity evaluation of Buchholzia coriacea stem bark. Fitoterapia. 2003;74(7-8):706-9.
Ajaiyeoba, E. O., Onocha, P. A., Nwozo, S. O., & Sama, W. (2003). Antimicrobial and cytotoxicity evaluation of Buchholzia coriacea stem bark. Fitoterapia, 74(7-8), 706-9.
Ajaiyeoba EO, et al. Antimicrobial and Cytotoxicity Evaluation of Buchholzia Coriacea Stem Bark. Fitoterapia. 2003;74(7-8):706-9. PubMed PMID: 14630180.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Antimicrobial and cytotoxicity evaluation of Buchholzia coriacea stem bark. AU - Ajaiyeoba,E O, AU - Onocha,P A, AU - Nwozo,S O, AU - Sama,W, PY - 2003/11/25/pubmed PY - 2004/3/31/medline PY - 2003/11/25/entrez SP - 706 EP - 9 JF - Fitoterapia JO - Fitoterapia VL - 74 IS - 7-8 N2 - Fractions prepared from the methanol extract of Buchholzia coriacea stem bark exhibited a high concentration-dependent antibacterial and antifungal activity compared to the standard antibiotics, ampicillin and tioconazole. In the brine shrimp lethality (BSL) assay, the methanol extract was found to be non-toxic with an LC(50) of 1031 microg/ml. The two main compounds present in the most active fraction were isolated and identified as lupeol and beta-sitosterol. SN - 0367-326X UR - https://www.unboundmedicine.com/medline/citation/14630180/Antimicrobial_and_cytotoxicity_evaluation_of_Buchholzia_coriacea_stem_bark_ DB - PRIME DP - Unbound Medicine ER -