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Incidence and prevalence of multiple sclerosis in Olmsted County, Minnesota, 1985-2000.

Abstract

BACKGROUND

Epidemiologic data for multiple sclerosis (MS) in Olmsted County, MN, have been recorded for almost 100 years and have indicated that the increasing prevalence rate was likely due in part to an increasing incidence rate.

METHODS

All cases of MS diagnosed from 1985 to 2000 were identified using the centralized diagnostic index at the Mayo Clinic and the Rochester Epidemiology Program Project, a shared database of all medical practitioners in the county. Patients were required to have established residency at least 1 year prior to diagnosis of MS. Results were also age- and sex-adjusted to control for shifts in the population structure.

RESULTS

The raw prevalence of MS was determined to be 177 per 100,000 on December 1, 2000, and the raw incidence rate was 7.5 per 100,000 person-years at risk from 1985 to 2000.

CONCLUSIONS

After age and sex adjustment to a common population, these prevalence and incidence rates of MS appear to have been stable rather than increasing over the past 20 years.

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  • Publisher Full Text
  • Authors+Show Affiliations

    ,

    Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA.

    , , , ,

    Source

    Neurology 61:10 2003 Nov 25 pg 1373-7

    MeSH

    Adolescent
    Adult
    Aged
    Female
    Humans
    Incidence
    Male
    Middle Aged
    Minnesota
    Multiple Sclerosis
    Prevalence

    Pub Type(s)

    Journal Article

    Language

    eng

    PubMed ID

    14638958

    Citation

    Mayr, W T., et al. "Incidence and Prevalence of Multiple Sclerosis in Olmsted County, Minnesota, 1985-2000." Neurology, vol. 61, no. 10, 2003, pp. 1373-7.
    Mayr WT, Pittock SJ, McClelland RL, et al. Incidence and prevalence of multiple sclerosis in Olmsted County, Minnesota, 1985-2000. Neurology. 2003;61(10):1373-7.
    Mayr, W. T., Pittock, S. J., McClelland, R. L., Jorgensen, N. W., Noseworthy, J. H., & Rodriguez, M. (2003). Incidence and prevalence of multiple sclerosis in Olmsted County, Minnesota, 1985-2000. Neurology, 61(10), pp. 1373-7.
    Mayr WT, et al. Incidence and Prevalence of Multiple Sclerosis in Olmsted County, Minnesota, 1985-2000. Neurology. 2003 Nov 25;61(10):1373-7. PubMed PMID: 14638958.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Incidence and prevalence of multiple sclerosis in Olmsted County, Minnesota, 1985-2000. AU - Mayr,W T, AU - Pittock,S J, AU - McClelland,R L, AU - Jorgensen,N W, AU - Noseworthy,J H, AU - Rodriguez,M, PY - 2003/11/26/pubmed PY - 2004/2/24/medline PY - 2003/11/26/entrez SP - 1373 EP - 7 JF - Neurology JO - Neurology VL - 61 IS - 10 N2 - BACKGROUND: Epidemiologic data for multiple sclerosis (MS) in Olmsted County, MN, have been recorded for almost 100 years and have indicated that the increasing prevalence rate was likely due in part to an increasing incidence rate. METHODS: All cases of MS diagnosed from 1985 to 2000 were identified using the centralized diagnostic index at the Mayo Clinic and the Rochester Epidemiology Program Project, a shared database of all medical practitioners in the county. Patients were required to have established residency at least 1 year prior to diagnosis of MS. Results were also age- and sex-adjusted to control for shifts in the population structure. RESULTS: The raw prevalence of MS was determined to be 177 per 100,000 on December 1, 2000, and the raw incidence rate was 7.5 per 100,000 person-years at risk from 1985 to 2000. CONCLUSIONS: After age and sex adjustment to a common population, these prevalence and incidence rates of MS appear to have been stable rather than increasing over the past 20 years. SN - 1526-632X UR - https://www.unboundmedicine.com/medline/citation/14638958/Incidence_and_prevalence_of_multiple_sclerosis_in_Olmsted_County_Minnesota_1985_2000_ L2 - http://www.neurology.org/cgi/pmidlookup?view=long&pmid=14638958 DB - PRIME DP - Unbound Medicine ER -