Tags

Type your tag names separated by a space and hit enter

Wernicke's encephalopathy: unusual contrast enhancement revealed by magnetic resonance imaging.
Eur J Med Res. 2003 Nov 12; 8(11):492-4.EJ

Abstract

Wernicke's encephalopathy is a serious neurologic disorder caused by vitamin-B1 or thiamine deficiency. The classical triad of clinical symptoms described by Wernicke (gait ataxia, ophthalmoplegia, and confusion) are found in only a third of patients upon initial examination. Typical findings upon MR imaging in patients with Wernicke's encephalopathy are well documented, with signal intensities in the medial thalami and periaqueductal regions of the midbrain. We report a case of Wernicke's encephalopathy revealing an unusual contrast enhancement. It is therefore important to note that the acute stage of Wernicke's encephalopathy may be associated with an intense contrast enhancement upon MR-imaging reflecting the disruption of the blood-brain barrier and inflammatory processes caused by thiamine deficiency. As a consequence from the guideline for managing Wernicke's encephalopathy by the Royal College of Physicians early B-vitamin treatment in suspected is recommended cases.

Authors+Show Affiliations

Department of Neurology, University of Essen, Hufelandstrasse 55, D-45122 Essen, Germany. ilker.kavuk@uni-essen.deNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

14644703

Citation

Kavuk, Ilker, et al. "Wernicke's Encephalopathy: Unusual Contrast Enhancement Revealed By Magnetic Resonance Imaging." European Journal of Medical Research, vol. 8, no. 11, 2003, pp. 492-4.
Kavuk I, Agelink MW, Gaertner T, et al. Wernicke's encephalopathy: unusual contrast enhancement revealed by magnetic resonance imaging. Eur J Med Res. 2003;8(11):492-4.
Kavuk, I., Agelink, M. W., Gaertner, T., Kastrup, O., Doerfler, A., Maschke, M., & Diener, H. C. (2003). Wernicke's encephalopathy: unusual contrast enhancement revealed by magnetic resonance imaging. European Journal of Medical Research, 8(11), 492-4.
Kavuk I, et al. Wernicke's Encephalopathy: Unusual Contrast Enhancement Revealed By Magnetic Resonance Imaging. Eur J Med Res. 2003 Nov 12;8(11):492-4. PubMed PMID: 14644703.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Wernicke's encephalopathy: unusual contrast enhancement revealed by magnetic resonance imaging. AU - Kavuk,Ilker, AU - Agelink,M W, AU - Gaertner,T, AU - Kastrup,O, AU - Doerfler,A, AU - Maschke,M, AU - Diener,H C, PY - 2003/12/4/pubmed PY - 2004/7/2/medline PY - 2003/12/4/entrez SP - 492 EP - 4 JF - European journal of medical research JO - Eur J Med Res VL - 8 IS - 11 N2 - Wernicke's encephalopathy is a serious neurologic disorder caused by vitamin-B1 or thiamine deficiency. The classical triad of clinical symptoms described by Wernicke (gait ataxia, ophthalmoplegia, and confusion) are found in only a third of patients upon initial examination. Typical findings upon MR imaging in patients with Wernicke's encephalopathy are well documented, with signal intensities in the medial thalami and periaqueductal regions of the midbrain. We report a case of Wernicke's encephalopathy revealing an unusual contrast enhancement. It is therefore important to note that the acute stage of Wernicke's encephalopathy may be associated with an intense contrast enhancement upon MR-imaging reflecting the disruption of the blood-brain barrier and inflammatory processes caused by thiamine deficiency. As a consequence from the guideline for managing Wernicke's encephalopathy by the Royal College of Physicians early B-vitamin treatment in suspected is recommended cases. SN - 0949-2321 UR - https://www.unboundmedicine.com/medline/citation/14644703/Wernicke's_encephalopathy:_unusual_contrast_enhancement_revealed_by_magnetic_resonance_imaging_ DB - PRIME DP - Unbound Medicine ER -