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[Microcirculation end effect of detralex in patients with chronic venous insufficiency of the lower extremities].
Angiol Sosud Khir. 2003; 9(3):60-5.AS

Abstract

Fourteen patients with chronic venous insufficiency (CVI) of the lower extremities, class 0-4 according to the CEAP (1995) were examined for microcirculation (MC) and effect of detralex, using biomicroscopy of the conjunctival vessels and capillaroscopy of the nail matrix, with detailed computed morphometry. In 7 patients, CVI was associated with truncal arterial hypertension and in 5 with type 2 diabetes mellitus. It has been established that in CVI patients, there were remarkable disorders of MC and regional circulation. In addition to regression of the clinical manifestations of CVI, administration of detralex given in courses to 12 patients noticeably refined both regional circulation in the lower extremities and systemic MC, marked by abatement of perivascular edema, an increase in the number of the functioning microvessels and flow acceleration in them. Also, there was marked the lowering of intramuscular red blood cell aggregation.

Authors+Show Affiliations

Faculty Therapy, Far Eastern Medical University, Khabarovsk, Russia.No affiliation info available

Pub Type(s)

Clinical Trial
English Abstract
Journal Article

Language

rus

PubMed ID

14657934

Citation

Sirotin, B Z., and K V. Zhmerenetskĭ. "[Microcirculation End Effect of Detralex in Patients With Chronic Venous Insufficiency of the Lower Extremities]." Angiologiia I Sosudistaia Khirurgiia = Angiology and Vascular Surgery, vol. 9, no. 3, 2003, pp. 60-5.
Sirotin BZ, Zhmerenetskĭ KV. [Microcirculation end effect of detralex in patients with chronic venous insufficiency of the lower extremities]. Angiol Sosud Khir. 2003;9(3):60-5.
Sirotin, B. Z., & Zhmerenetskĭ, K. V. (2003). [Microcirculation end effect of detralex in patients with chronic venous insufficiency of the lower extremities]. Angiologiia I Sosudistaia Khirurgiia = Angiology and Vascular Surgery, 9(3), 60-5.
Sirotin BZ, Zhmerenetskĭ KV. [Microcirculation End Effect of Detralex in Patients With Chronic Venous Insufficiency of the Lower Extremities]. Angiol Sosud Khir. 2003;9(3):60-5. PubMed PMID: 14657934.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Microcirculation end effect of detralex in patients with chronic venous insufficiency of the lower extremities]. AU - Sirotin,B Z, AU - Zhmerenetskĭ,K V, PY - 2003/12/6/pubmed PY - 2004/5/5/medline PY - 2003/12/6/entrez SP - 60 EP - 5 JF - Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery JO - Angiol Sosud Khir VL - 9 IS - 3 N2 - Fourteen patients with chronic venous insufficiency (CVI) of the lower extremities, class 0-4 according to the CEAP (1995) were examined for microcirculation (MC) and effect of detralex, using biomicroscopy of the conjunctival vessels and capillaroscopy of the nail matrix, with detailed computed morphometry. In 7 patients, CVI was associated with truncal arterial hypertension and in 5 with type 2 diabetes mellitus. It has been established that in CVI patients, there were remarkable disorders of MC and regional circulation. In addition to regression of the clinical manifestations of CVI, administration of detralex given in courses to 12 patients noticeably refined both regional circulation in the lower extremities and systemic MC, marked by abatement of perivascular edema, an increase in the number of the functioning microvessels and flow acceleration in them. Also, there was marked the lowering of intramuscular red blood cell aggregation. SN - 1027-6661 UR - https://www.unboundmedicine.com/medline/citation/14657934/[Microcirculation_end_effect_of_detralex_in_patients_with_chronic_venous_insufficiency_of_the_lower_extremities]_ L2 - https://medlineplus.gov/varicoseveins.html DB - PRIME DP - Unbound Medicine ER -