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Pneumonia vaccine trials at Tari.
P N G Med J. 2002 Mar-Jun; 45(1-2):44-50.PN

Abstract

Pneumonia is the commonest cause of death of children in Papua New Guinea (PNG). At Tari pneumonia is most commonly caused by Streptococcus pneumoniae and Haemophilus influenzae, which set up rapid severe infections in the lungs that require urgent treatment. In rural PNG, however, treatment is often delayed. Penicillin-resistant forms of these bacteria are on the increase. It is therefore important to have another means of protection against this serious disease. This paper describes three field trials of a vaccine against the commonest serotypes of S. pneumoniae found in PNG. The trials show that a pneumococcal vaccine can prevent deaths from uncomplicated acute lower respiratory tract infection in small children and adults. It is likely that the vaccine does this by limiting the replication of bacteria in the lungs and thus limiting their spread to other parts of the body.

Authors+Show Affiliations

Australian Centre for International and Tropical Health and Nutrition, Queensland Medical School, University of Queensland.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

14658827

Citation

Riley, Ian D.. "Pneumonia Vaccine Trials at Tari." Papua and New Guinea Medical Journal, vol. 45, no. 1-2, 2002, pp. 44-50.
Riley ID. Pneumonia vaccine trials at Tari. P N G Med J. 2002;45(1-2):44-50.
Riley, I. D. (2002). Pneumonia vaccine trials at Tari. Papua and New Guinea Medical Journal, 45(1-2), 44-50.
Riley ID. Pneumonia Vaccine Trials at Tari. P N G Med J. 2002 Mar-Jun;45(1-2):44-50. PubMed PMID: 14658827.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Pneumonia vaccine trials at Tari. A1 - Riley,Ian D, PY - 2003/12/9/pubmed PY - 2004/1/6/medline PY - 2003/12/9/entrez SP - 44 EP - 50 JF - Papua and New Guinea medical journal JO - P N G Med J VL - 45 IS - 1-2 N2 - Pneumonia is the commonest cause of death of children in Papua New Guinea (PNG). At Tari pneumonia is most commonly caused by Streptococcus pneumoniae and Haemophilus influenzae, which set up rapid severe infections in the lungs that require urgent treatment. In rural PNG, however, treatment is often delayed. Penicillin-resistant forms of these bacteria are on the increase. It is therefore important to have another means of protection against this serious disease. This paper describes three field trials of a vaccine against the commonest serotypes of S. pneumoniae found in PNG. The trials show that a pneumococcal vaccine can prevent deaths from uncomplicated acute lower respiratory tract infection in small children and adults. It is likely that the vaccine does this by limiting the replication of bacteria in the lungs and thus limiting their spread to other parts of the body. SN - 0031-1480 UR - https://www.unboundmedicine.com/medline/citation/14658827/Pneumonia_vaccine_trials_at_Tari_ L2 - https://medlineplus.gov/haemophilusinfections.html DB - PRIME DP - Unbound Medicine ER -