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Can the consumption of tomatoes or lycopene reduce cancer risk?
Integr Cancer Ther. 2002 Jun; 1(2):121-32; discussion 132.IC

Abstract

Lycopene, a natural antioxidant found predominantly in tomato products, is attracting attention as a cancer prevention agent. Serum and dietary lycopene levels have been found to be inversely related to the incidence of several types of cancer, including prostate cancer. Although the antioxidant properties of lycopene are thought to be primarily responsible for its apparent beneficial effects, other mechanisms may also be involved. We outline the possible mechanisms of action of lycopene and review the current findings of in vitro and in vivo studies in cancer prevention and to some extent treatment. We examine the epidemiologic evidence regarding consumption of tomato and tomato products with the risk of cancer at various sites. Data suggest lycopene may account for or contribute to chemoprevention, but this hypothesis requires further study. Numerous other potentially beneficial compounds are present in tomatoes and complex interactions among multiple components may contribute to the anticancer properties of tomatoes.

Authors+Show Affiliations

Department of Human Nutrition (M/C 517), 1919 W. Taylor Street, University of Illinois at Chicago, Chicago, IL 60612, USA.No affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

14664737

Citation

Hwang, Eun-Sun, and Phyllis E. Bowen. "Can the Consumption of Tomatoes or Lycopene Reduce Cancer Risk?" Integrative Cancer Therapies, vol. 1, no. 2, 2002, pp. 121-32; discussion 132.
Hwang ES, Bowen PE. Can the consumption of tomatoes or lycopene reduce cancer risk? Integr Cancer Ther. 2002;1(2):121-32; discussion 132.
Hwang, E. S., & Bowen, P. E. (2002). Can the consumption of tomatoes or lycopene reduce cancer risk? Integrative Cancer Therapies, 1(2), 121-32; discussion 132.
Hwang ES, Bowen PE. Can the Consumption of Tomatoes or Lycopene Reduce Cancer Risk. Integr Cancer Ther. 2002;1(2):121-32; discussion 132. PubMed PMID: 14664737.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Can the consumption of tomatoes or lycopene reduce cancer risk? AU - Hwang,Eun-Sun, AU - Bowen,Phyllis E, PY - 2003/12/11/pubmed PY - 2004/3/3/medline PY - 2003/12/11/entrez SP - 121-32; discussion 132 JF - Integrative cancer therapies JO - Integr Cancer Ther VL - 1 IS - 2 N2 - Lycopene, a natural antioxidant found predominantly in tomato products, is attracting attention as a cancer prevention agent. Serum and dietary lycopene levels have been found to be inversely related to the incidence of several types of cancer, including prostate cancer. Although the antioxidant properties of lycopene are thought to be primarily responsible for its apparent beneficial effects, other mechanisms may also be involved. We outline the possible mechanisms of action of lycopene and review the current findings of in vitro and in vivo studies in cancer prevention and to some extent treatment. We examine the epidemiologic evidence regarding consumption of tomato and tomato products with the risk of cancer at various sites. Data suggest lycopene may account for or contribute to chemoprevention, but this hypothesis requires further study. Numerous other potentially beneficial compounds are present in tomatoes and complex interactions among multiple components may contribute to the anticancer properties of tomatoes. SN - 1534-7354 UR - https://www.unboundmedicine.com/medline/citation/14664737/Can_the_consumption_of_tomatoes_or_lycopene_reduce_cancer_risk L2 - http://journals.sagepub.com/doi/full/10.1177/153473540200100203?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -