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[Recent intervention studies with antihypertensive drugs and their influence on guidelines].
Med Klin (Munich). 2003 Dec 15; 98(12):771-5.MK

Abstract

Antihypertensive therapy improves the prognosis of essential hypertension. Therapy reduces mortality and decreases the incidence of myocardial infarction, sudden cardiac death and stroke. Target blood pressure in patients with essential hypertension are levels < or = 140/90 mmHg. In patients with essential hypertension and concomitant diabetes mellitus type 2, blood pressure should be lowered to < or = 130/80 mmHg. Diuretics, beta-blockers, calcium antagonists, angiotensin-converting enyzme (ACE) inhibitors, and angiotensin I (AT(1)) antagonists may nowadays be regarded as drugs of first choice in the treatment of essential hypertension. The Joint National Committee in the USA recommends to start treatment with a thiazide diuretic. A Guidelines Committee of European Society of Hypertension-European Society of Cardiology considers the Endgroups of drugs mentioned above to be equally suitable for the initiation and maintenance of antihypertensive therapy. Both groups of experts agree that in the majority of patients with essential hypertension, a combination of two or more drugs is required to reach target blood pressure. Both groups of experts emphasize that the main benefits of antihypertensive therapy are due to decreasing blood pressure per se.

Authors+Show Affiliations

Medizinische Klinik und Poliklinik D, Universitätsklinikum, Muenster. karl-heinz.rahn@ukmuenster.de

Pub Type(s)

Comparative Study
English Abstract
Journal Article
Review

Language

ger

PubMed ID

14685679

Citation

Rahn, Karl-Heinz. "[Recent Intervention Studies With Antihypertensive Drugs and Their Influence On Guidelines]." Medizinische Klinik (Munich, Germany : 1983), vol. 98, no. 12, 2003, pp. 771-5.
Rahn KH. [Recent intervention studies with antihypertensive drugs and their influence on guidelines]. Med Klin (Munich). 2003;98(12):771-5.
Rahn, K. H. (2003). [Recent intervention studies with antihypertensive drugs and their influence on guidelines]. Medizinische Klinik (Munich, Germany : 1983), 98(12), 771-5.
Rahn KH. [Recent Intervention Studies With Antihypertensive Drugs and Their Influence On Guidelines]. Med Klin (Munich). 2003 Dec 15;98(12):771-5. PubMed PMID: 14685679.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Recent intervention studies with antihypertensive drugs and their influence on guidelines]. A1 - Rahn,Karl-Heinz, PY - 2003/10/13/received PY - 2003/10/13/accepted PY - 2003/12/20/pubmed PY - 2004/3/20/medline PY - 2003/12/20/entrez SP - 771 EP - 5 JF - Medizinische Klinik (Munich, Germany : 1983) JO - Med. Klin. (Munich) VL - 98 IS - 12 N2 - Antihypertensive therapy improves the prognosis of essential hypertension. Therapy reduces mortality and decreases the incidence of myocardial infarction, sudden cardiac death and stroke. Target blood pressure in patients with essential hypertension are levels < or = 140/90 mmHg. In patients with essential hypertension and concomitant diabetes mellitus type 2, blood pressure should be lowered to < or = 130/80 mmHg. Diuretics, beta-blockers, calcium antagonists, angiotensin-converting enyzme (ACE) inhibitors, and angiotensin I (AT(1)) antagonists may nowadays be regarded as drugs of first choice in the treatment of essential hypertension. The Joint National Committee in the USA recommends to start treatment with a thiazide diuretic. A Guidelines Committee of European Society of Hypertension-European Society of Cardiology considers the Endgroups of drugs mentioned above to be equally suitable for the initiation and maintenance of antihypertensive therapy. Both groups of experts agree that in the majority of patients with essential hypertension, a combination of two or more drugs is required to reach target blood pressure. Both groups of experts emphasize that the main benefits of antihypertensive therapy are due to decreasing blood pressure per se. SN - 0723-5003 UR - https://www.unboundmedicine.com/medline/citation/14685679/[Recent_intervention_studies_with_antihypertensive_drugs_and_their_influence_on_guidelines]_ L2 - https://dx.doi.org/10.1007/s00063-003-1323-4 DB - PRIME DP - Unbound Medicine ER -