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Scanning electron microscopic examination of third metacarpal/third metatarsal bone failure surfaces in thoroughbred racehorses with condylar fracture.
Vet Surg. 2004 Jan-Feb; 33(1):2-10.VS

Abstract

OBJECTIVE

To examine the fracture failure surfaces from Thoroughbred horses that had sustained a catastrophic condylar fracture.

SAMPLE POPULATION

Bone specimens from the failure surface were obtained from 12 Thoroughbred racehorses with catastrophic injury and 2 non-racing horses with accidental long bone fracture.

METHODS

Bone specimens from the failure surface of each fracture were incubated with gold microspheres to label microcracks before examination at x50 to x60,000 using scanning electron microscopy. Microcracking at the failure surface was assessed using a visual analog scale.

RESULTS

Branching arrays or clusters of microcracks were seen over a range of magnifications in adapted subchondral bone in the distal end of the MC3/MT3 bone from racing Thoroughbreds with a catastrophic displaced condylar fracture. In the palmar/plantar region, microcracking was associated with the formation of an array of macroscopic cracks in the condylar groove. A different pattern of microcracking was seen in specimens of bone from distal metaphyseal and diaphyseal MC3/MT3 failure surfaces from Thoroughbred racehorses with catastrophic fracture and non-racing horses with an accidental diaphyseal long bone fracture. Few microcracks were seen and typically did not form branching arrays.

CONCLUSION

These data suggest that propagation of condylar fracture in Thoroughbred racehorses is initiated by the formation of nanoscale microcracks in adapted subchondral bone that form during exercise-induced bone adaptation.

CLINICAL RELEVANCE

Accumulation and coalescence of branching microcracks into arrays or clusters appears to eventually lead to the development of macroscopic subchondral cracks in the condylar groove and initiation of a condylar fracture.

Authors+Show Affiliations

Comparative Orthopaedic Research Laboratory, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI 53706, USA.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

14687180

Citation

Stepnik, Matthew W., et al. "Scanning Electron Microscopic Examination of Third Metacarpal/third Metatarsal Bone Failure Surfaces in Thoroughbred Racehorses With Condylar Fracture." Veterinary Surgery : VS, vol. 33, no. 1, 2004, pp. 2-10.
Stepnik MW, Radtke CL, Scollay MC, et al. Scanning electron microscopic examination of third metacarpal/third metatarsal bone failure surfaces in thoroughbred racehorses with condylar fracture. Vet Surg. 2004;33(1):2-10.
Stepnik, M. W., Radtke, C. L., Scollay, M. C., Oshel, P. E., Albrecht, R. M., Santschi, E. M., Markel, M. D., & Muir, P. (2004). Scanning electron microscopic examination of third metacarpal/third metatarsal bone failure surfaces in thoroughbred racehorses with condylar fracture. Veterinary Surgery : VS, 33(1), 2-10.
Stepnik MW, et al. Scanning Electron Microscopic Examination of Third Metacarpal/third Metatarsal Bone Failure Surfaces in Thoroughbred Racehorses With Condylar Fracture. Vet Surg. 2004 Jan-Feb;33(1):2-10. PubMed PMID: 14687180.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Scanning electron microscopic examination of third metacarpal/third metatarsal bone failure surfaces in thoroughbred racehorses with condylar fracture. AU - Stepnik,Matthew W, AU - Radtke,Catherine L, AU - Scollay,Mary C, AU - Oshel,Philip E, AU - Albrecht,Ralph M, AU - Santschi,Elizabeth M, AU - Markel,Mark D, AU - Muir,Peter, PY - 2003/12/23/pubmed PY - 2004/3/31/medline PY - 2003/12/23/entrez SP - 2 EP - 10 JF - Veterinary surgery : VS JO - Vet Surg VL - 33 IS - 1 N2 - OBJECTIVE: To examine the fracture failure surfaces from Thoroughbred horses that had sustained a catastrophic condylar fracture. SAMPLE POPULATION: Bone specimens from the failure surface were obtained from 12 Thoroughbred racehorses with catastrophic injury and 2 non-racing horses with accidental long bone fracture. METHODS: Bone specimens from the failure surface of each fracture were incubated with gold microspheres to label microcracks before examination at x50 to x60,000 using scanning electron microscopy. Microcracking at the failure surface was assessed using a visual analog scale. RESULTS: Branching arrays or clusters of microcracks were seen over a range of magnifications in adapted subchondral bone in the distal end of the MC3/MT3 bone from racing Thoroughbreds with a catastrophic displaced condylar fracture. In the palmar/plantar region, microcracking was associated with the formation of an array of macroscopic cracks in the condylar groove. A different pattern of microcracking was seen in specimens of bone from distal metaphyseal and diaphyseal MC3/MT3 failure surfaces from Thoroughbred racehorses with catastrophic fracture and non-racing horses with an accidental diaphyseal long bone fracture. Few microcracks were seen and typically did not form branching arrays. CONCLUSION: These data suggest that propagation of condylar fracture in Thoroughbred racehorses is initiated by the formation of nanoscale microcracks in adapted subchondral bone that form during exercise-induced bone adaptation. CLINICAL RELEVANCE: Accumulation and coalescence of branching microcracks into arrays or clusters appears to eventually lead to the development of macroscopic subchondral cracks in the condylar groove and initiation of a condylar fracture. SN - 0161-3499 UR - https://www.unboundmedicine.com/medline/citation/14687180/Scanning_electron_microscopic_examination_of_third_metacarpal/third_metatarsal_bone_failure_surfaces_in_thoroughbred_racehorses_with_condylar_fracture_ L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0161-3499&date=2004&volume=33&issue=1&spage=2 DB - PRIME DP - Unbound Medicine ER -